N/A
N=26
The Use of Specialised Amino Acid Mixture in Pressure Ulcer Wound Healing Rates- A Placebo Controlled Trial
Pressure Ulcer
Bottom Line
View on ClinicalTrials.gov: NCT01090076 ↗Enrolled (actual)
26
Serious AEs
0.0%
Results posted
Jun 2013
Primary outcome: Primary: % Viable Tissue — 43.06; 25.94 Percentage of viable tissue — p=0.023
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Abound (7 g of Arginine, 7 g Glutamine and 1.2 g HMB) (Dietary_supplement)
- Age
- Adult, Older Adult · 21+ yrs
- Sex
- All
- Sponsor
- Changi General Hospital
- Primary completion
- Jul 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY % Viable Tissue |
43.06; 25.94 | 0.023 sig |
| PRIMARY % Wound Area Week 1 |
-15.37; -13.68 | 0.877 |
| PRIMARY % Wound Area Week 2 |
-27.50; -37.54 | 0.44 |
Summary
This research aims to address the gap in the studies done and test the effects of a commercial mixture of 7 g of Arginine, 7 g Glutamine and 1.2 g HMB* twice a day on hard to heal pressure ulcers in an Asian patient cohort in an acute healthcare setting.
Eligibility Criteria
Inclusion Criteria
- Patients with pressure ulcers stage II, III or IV, non-healing admitted to Changi General Hospital for > 2 weeks
- Patients who are able to attend outpatient follow-up appointments for dietary and wound review
Exclusion Criteria
- Age 7.0%)
- Patients on Total Parenteral Nutrition
- Patients in MICU/ SICU/ Medically Unstable/ Palliative Care
- Patients with severe Sepsis
- Length of stay 70% EER and/or Fluid intake 30ml/kg BW
- Patients who require protein restriction
- Patients who are unable to give consent (absence of next-of-kin)
Data sourced from ClinicalTrials.gov (NCT01090076). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.