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Home › Conditions › Pressure Ulcer

Pressure Ulcer

Part of Pressure injury

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Pressure Ulcer

34 trials tracked for Pressure Ulcer: 4 in phase 3 or 4.

34Trials tracked
4Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 3 Phase 3 1 Phase 2 2 Other / NA 28
  1. Phase 4 A Multi-centre Evaluation of the Performance of Window Dressings on Subjects With High Risk Pressure Ulceration Completed
  2. Phase 4 Pressure Ulcer Healing With Microcyn Completed
  3. Phase 4 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue Completed
  4. Phase 3 Pressure Ulcer Prevention in Ventilated Patients Using Two Repositioning Regimens Completed
  5. Phase 2 Study of Thymosin Beta 4 in Patients With Pressure Ulcers Completed
  6. Phase 2 Insulin Complexation With Hydroxypropyl-beta-cyclodextrin: Use of the Complex in Gel for Healing of Pressure Ulcers Completed
Show 28 more trials
  1. N/A Usability Validation of Patient Monitoring Device for Pressure Injury Prevention and Fall Detection Completed
  2. N/A An RCT on Preventing Pressure Ulcers With Wheelchair Seat Cushions Completed
  3. N/A Nutritional Support in Pressure Ulcer Patients Completed
  4. N/A Effects of Different Support Surfaces on the Properties Skin After Loading Completed
  5. N/A Polyurethane Foam on the Sacrum for Prevention Completed
  6. N/A An RCT on Support Surfaces for Pressure Ulcer Prevention Completed
  7. N/A Post Market Clinical Follow-up Investigation to Evaluate Performance and Safety on Pressure Ulcers, PU, When Using Exufiber as Intended Completed
  8. N/A EmoLED Medical Device Treatment of Second and Third Stage Pressure Ulcers Completed
  9. N/A Alternating Pressure Overlay on Weight Bearing Tissue Tolerance in People With Spinal Cord Injury Completed
  10. N/A Comparison Between a Novel Proning Pillow System and Standard Pillows Completed
  11. N/A Self-Management to Prevent Ulcers in Veterans With SCI (Spinal Cord Injury) Completed
  12. N/A Polyurethane Foam on the Heel for Prevention in Children Completed
  13. N/A Evaluation Of An Advanced Borderless Dressing Completed
  14. N/A A Pilot Study to Assess the DynaSense System Completed
  15. N/A Silicone Adhesive Multilayer Foam Dressings to Prevent Pressure Ulcer Completed
  16. N/A Comparison of Nasal and Forehead Oximetry in Critically Ill Patients at Risk for Decreased Peripheral Perfusion Completed
  17. N/A P400 for Stage II-IV Pressure Ulcers in Home and Extended Care Completed
  18. N/A Pilot Study of Incidence and Change in Existing Pressure Ulcers: TC500 Bed Compared With Standard Beds Completed
  19. N/A Peripheral Catheter Pressure Ulcer Prevention in Pediatry : Use of Compresses Versus Standard Care Completed
  20. N/A Development of Technologies to Increase In-Seat Movement to Prevent Sitting-Acquired Pressure Injuries in Wheelchair Users Completed
  21. N/A Optimal Patient Turning for Reducing Hospital Acquired Pressure Ulcers Completed
  22. N/A Silk-Like Bed Linens for Prevention of Unit-Acquired Ulcers Completed
  23. N/A Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds Completed
  24. N/A The Use of Specialised Amino Acid Mixture in Pressure Ulcer Wound Healing Rates- A Placebo Controlled Trial Completed
  25. N/A Evaluation of the SEM Scanner 200 for the Detection of Early Pressure Ulcers: A Multi-Site Longitudinal Study Completed
  26. N/A Fluid Immersion Simulation (FIS) System Versus Air Fluidized Bed (AFB) System for Pressure Ulcers Completed
  27. N/A Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention Completed
  28. N/A Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Injuries Completed

Showing the 34 most-cited and recently-updated of 34 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Pressure Ulcer: what the trials found

New evidence suggests that utilizing a peripheral venous catheter with compress under the catheter-extension tube junction may impact the incidence of pressure ulcers graded $\geq$1 on the NPUAP scale 1.

TheraHoney HD has been shown to result in a 63.1% wound healing rate compared to 6.1% in the control group 2. Microcyn demonstrated significant reductions in pressure ulcer size (length x width x depth) at 4, 8, and 12 weeks post-baseline compared to the control group 3.

Repositioning interventions were evaluated for their impact on the incidence of Pressure Ulcer (PU) Grade $\geq$ II 5.

Recent results — preliminary, needs further review

  • The use of a peripheral venous catheter with compress under the junction is a newly identified intervention for pressure ulcer management 1.

For the clinician treating this condition

  • TheraHoney HD shows a high percentage of wound healing compared to standard care 2.
  • Microcyn treatment resulted in significantly smaller pressure ulcer dimensions at 4, 8, and 12 weeks post-baseline 3.
  • Repositioning is an established intervention for managing the incidence of Grade $\geq$ II pressure ulcers 5.

AI synthesis of 4 cited trials, updated Jun 21, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
STAIR OF KNOWLEDGE intervention shows feasibility in Swedish nursing homes for multiple geriatric risks
Geriatrics & Aging RCT
STAIR OF KNOWLEDGE intervention shows feasibility in Swedish nursing homes for multiple geriatric risks New Program Shows Promise for Improving Care in Nursing Homes
This cluster randomized pilot study tested the STAIR OF KNOWLEDGE intervention in 8 Swedish nursing homes (309 older persons). All homes com…
A new program helps nursing home staff create and carry out care plans for seniors at risk of pressure ulcers and malnutrition.
Jun 27, 2026
Stem cell–derived secretome may offer an alternative to live cell therapies for chronic wound healing
Drug Pipeline Sys. Review
Stem cell–derived secretome may offer an alternative to live cell therapies for chronic wound healing Review compares stem cell secretome to live cell therapies for leg ulcers
This narrative review synthesizes evidence on stem cell–derived secretome versus live cell therapies for diabetic, venous leg, and pressure …
A review looks at how stem cell secretome stacks up against live cell therapies for healing diabetic, venous, and pressure ulcers.
Frontiers Jun 3, 2026
Gradient warning nursing procedure reduced pressure ulcers in prone orthopedic surgery patients
Oncology RCT
Gradient warning nursing procedure reduced pressure ulcers in prone orthopedic surgery patients New Nursing Method Cuts Bed Sores in Half
This retrospective cohort study evaluated 126 prone-positioned orthopedic surgery patients comparing a gradient warning nursing procedure (G…
A new nursing warning system slashes bed sore rates by 89% for spine surgery patients lying on their stomachs.
Frontiers Apr 13, 2026

Research across Pressure injury

Related studies from across the Pressure injury family.

Meta-analysis finds very uncertain evidence for CO therapy in wound healing
Diabetes & Endocrinology Meta-analysis
Meta-analysis finds very uncertain evidence for CO therapy in wound healing Carbon Dioxide Therapy May Help Stubborn Wounds Heal Faster
This meta-analysis of 127 wounds/participants evaluated highly concentrated carbon dioxide therapy for diabetic foot ulcers and pressure inj…
A new review suggests highly concentrated carbon dioxide therapy may help chronic wounds heal better, but the evidence is still early.
May 11, 2026
Systematic review and meta-analysis links prior flap reconstruction and injury level to pressure injury recurrence in SCI patients
Physical Medicine & Rehab Meta-analysis
Systematic review and meta-analysis links prior flap reconstruction and injury level to pressure injury recurrence in SCI patients Prior flap surgery raises complication risk for spinal cord injury patients
This systematic review and meta-analysis evaluated risk factors for acute postoperative complications and pressure injury recurrence in 1976…
Past flap reconstruction surgery significantly increases the risk of complications and pressure injury recurrence for spinal cord injury pat…
May 1, 2026