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Pressure Ulcer

Part of Pressure injury

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Pressure Ulcer

34 trials tracked for Pressure Ulcer: 4 in phase 3 or 4.

34Trials tracked

4Phase 3 & 4

0Recruiting

0With published results

Phase distribution

Phase 4 3 Phase 3 1 Phase 2 2 Other / NA 28

Phase 4 A Multi-centre Evaluation of the Performance of Window Dressings on Subjects With High Risk Pressure Ulceration Completed
Phase 4 Pressure Ulcer Healing With Microcyn Completed
Phase 4 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue Completed
Phase 3 Pressure Ulcer Prevention in Ventilated Patients Using Two Repositioning Regimens Completed
Phase 2 Study of Thymosin Beta 4 in Patients With Pressure Ulcers Completed
Phase 2 Insulin Complexation With Hydroxypropyl-beta-cyclodextrin: Use of the Complex in Gel for Healing of Pressure Ulcers Completed

Show 28 more trials

N/A Usability Validation of Patient Monitoring Device for Pressure Injury Prevention and Fall Detection Completed
N/A An RCT on Preventing Pressure Ulcers With Wheelchair Seat Cushions Completed
N/A Nutritional Support in Pressure Ulcer Patients Completed
N/A Effects of Different Support Surfaces on the Properties Skin After Loading Completed
N/A Polyurethane Foam on the Sacrum for Prevention Completed
N/A An RCT on Support Surfaces for Pressure Ulcer Prevention Completed
N/A Post Market Clinical Follow-up Investigation to Evaluate Performance and Safety on Pressure Ulcers, PU, When Using Exufiber as Intended Completed
N/A EmoLED Medical Device Treatment of Second and Third Stage Pressure Ulcers Completed
N/A Alternating Pressure Overlay on Weight Bearing Tissue Tolerance in People With Spinal Cord Injury Completed
N/A Comparison Between a Novel Proning Pillow System and Standard Pillows Completed
N/A Self-Management to Prevent Ulcers in Veterans With SCI (Spinal Cord Injury) Completed
N/A Polyurethane Foam on the Heel for Prevention in Children Completed
N/A Evaluation Of An Advanced Borderless Dressing Completed
N/A A Pilot Study to Assess the DynaSense System Completed
N/A Silicone Adhesive Multilayer Foam Dressings to Prevent Pressure Ulcer Completed
N/A Comparison of Nasal and Forehead Oximetry in Critically Ill Patients at Risk for Decreased Peripheral Perfusion Completed
N/A P400 for Stage II-IV Pressure Ulcers in Home and Extended Care Completed
N/A Pilot Study of Incidence and Change in Existing Pressure Ulcers: TC500 Bed Compared With Standard Beds Completed
N/A Peripheral Catheter Pressure Ulcer Prevention in Pediatry : Use of Compresses Versus Standard Care Completed
N/A Development of Technologies to Increase In-Seat Movement to Prevent Sitting-Acquired Pressure Injuries in Wheelchair Users Completed
N/A Optimal Patient Turning for Reducing Hospital Acquired Pressure Ulcers Completed
N/A Silk-Like Bed Linens for Prevention of Unit-Acquired Ulcers Completed
N/A Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds Completed
N/A The Use of Specialised Amino Acid Mixture in Pressure Ulcer Wound Healing Rates- A Placebo Controlled Trial Completed
N/A Evaluation of the SEM Scanner 200 for the Detection of Early Pressure Ulcers: A Multi-Site Longitudinal Study Completed
N/A Fluid Immersion Simulation (FIS) System Versus Air Fluidized Bed (AFB) System for Pressure Ulcers Completed
N/A Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention Completed
N/A Comparing Concomitant Use of ACell MicroMatrix® and ACell Cytal™ to Standard of Care in Stage 3 or 4 Pressure Injuries Completed

Showing the 34 most-cited and recently-updated of 34 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Pressure Ulcer: what the trials found

New evidence suggests that utilizing a peripheral venous catheter with compress under the catheter-extension tube junction may impact the incidence of pressure ulcers graded $\geq$1 on the NPUAP scale ¹.

TheraHoney HD has been shown to result in a 63.1% wound healing rate compared to 6.1% in the control group ². Microcyn demonstrated significant reductions in pressure ulcer size (length x width x depth) at 4, 8, and 12 weeks post-baseline compared to the control group ³.

Repositioning interventions were evaluated for their impact on the incidence of Pressure Ulcer (PU) Grade $\geq$ II ⁵.

Recent results — preliminary, needs further review

The use of a peripheral venous catheter with compress under the junction is a newly identified intervention for pressure ulcer management ¹.

For the clinician treating this condition

TheraHoney HD shows a high percentage of wound healing compared to standard care ².
Microcyn treatment resulted in significantly smaller pressure ulcer dimensions at 4, 8, and 12 weeks post-baseline ³.
Repositioning is an established intervention for managing the incidence of Grade $\geq$ II pressure ulcers ⁵.

AI synthesis of 4 cited trials, updated Jun 21, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

Research across Pressure injury

Related studies from across the Pressure injury family.

Risk factors and prevention strategies for medical device-related pressure injuries in critically ill patients

Primary Care & Family Medicine Sys. Review

Risk factors and prevention strategies for medical device-related pressure injuries in critically ill patients New research identifies key risks for medical device pressure injuries

This scoping review synthesizes evidence regarding medical device-related pressure injuries (MDRPIs) in critically ill patients. It identifi…

Critically ill patients often suffer skin damage from medical devices. New data highlights specific risk factors and nursing measures to hel…

Frontiers Aug 30, 2026

Meta-analysis finds very uncertain evidence for CO therapy in wound healing

Diabetes & Endocrinology Meta-analysis

Meta-analysis finds very uncertain evidence for CO therapy in wound healing Carbon Dioxide Therapy May Help Stubborn Wounds Heal Faster

This meta-analysis of 127 wounds/participants evaluated highly concentrated carbon dioxide therapy for diabetic foot ulcers and pressure inj…

A new review suggests highly concentrated carbon dioxide therapy may help chronic wounds heal better, but the evidence is still early.

Systematic review and meta-analysis links prior flap reconstruction and injury level to pressure injury recurrence in SCI patients

Physical Medicine & Rehab Meta-analysis

Systematic review and meta-analysis links prior flap reconstruction and injury level to pressure injury recurrence in SCI patients Prior flap surgery raises complication risk for spinal cord injury patients

This systematic review and meta-analysis evaluated risk factors for acute postoperative complications and pressure injury recurrence in 1976…

Past flap reconstruction surgery significantly increases the risk of complications and pressure injury recurrence for spinal cord injury pat…