N/A
N=9
Exercise as an Adjuvant to Aphasia Therapy
Aphasia
Bottom Line
View on ClinicalTrials.gov: NCT01113879 ↗Enrolled (actual)
9
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcome: Primary: Change in Picture Naming Abilities as Measured by Tau U Effect Size Weighted Means — 0.83; 0.75; 0.88; 0.77 Tau U effect size weighted mean — p=< 0.001
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Aerobic exercise (Behavioral); Stretching (Behavioral)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Jul 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Picture Naming Abilities as Measured by Tau U Effect Size Weighted Means |
0.83; 0.75; 0.88; 0.77 | < 0.001 sig |
| SECONDARY Change in Serum Brain-derived Neurotrophic Factor (BDNF) Levels With Exercise |
0; 1; 4; 0; 4; 0 | — |
Summary
The purpose of the study is to reveal if individuals who participate in aerobic activity demonstrate greater improvement in language abilities than patients who do not participate in aerobic activity.
Eligibility Criteria
Inclusion Criteria
- Post-stroke aphasia
- at least 6 months post-stroke
- at least minimally intact auditory verbal comprehension
- pre-morbidly right handed
- native English speaker
Exclusion Criteria
- contraindications for fMRI (metal implants, claustrophobia)
- inability to pass an exercise tolerance test
- significant depression
- uncorrected hearing or vision problems
- severe apraxia of speech
- regularly perform 20 minutes of cardiovascular exercise 3 times per week
Data sourced from ClinicalTrials.gov (NCT01113879). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.