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N/A N=140 Randomized Single-blind Prevention

Reducing Risk of Recurrence

Stroke · TIA · Hypertension · Hyperlipidemia

Enrolled (actual)
140
Serious AEs
2.1%
Results posted
Oct 2016
Primary outcome: Primary: Systolic Blood Pressure — 130.83; 133.67 mm Hg — p=0.29

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
TI (Behavioral); AP (Behavioral)
Age
Adult, Older Adult · 21+ yrs
Sex
All
Sponsor
VA Office of Research and Development
Primary completion
Jun 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Systolic Blood Pressure
130.83; 133.67 0.29
SECONDARY
Dietary Sodium
11; 18; 52; 52 0.25
SECONDARY
Total Cholesterol/High Density Lipoprotein Ratio
3.47; 3.21 0.11
SECONDARY
Exercise Adherence
2.50; 2.75 0.81
SECONDARY
Antihypertensive/ Lipid-lowering Medication Adherence
3.58; 3.43 0.12

Summary

Adults who have had a previous stroke or transient ischemic attack (TIA) remain at risk for having a second serious event, especially if they have uncontrolled blood pressure or cholesterol. However, many patients have difficulty following treatment recommendations for lowering blood pressure and cholesterol. The purpose of this research project is to evaluate the effect of 2 booster sessions of an educational counseling intervention on how well adults who have already participated in a 6-month clinical trial had a stroke or transient ischemic attack (TIA) are able to follow a treatment plan and control their blood pressure and cholesterol levels. We will also examine how effective this intervention is in improving adherence to diet, medication, and physical activity recommendations for adults who have had a prior stroke or TIA.

Eligibility Criteria

Inclusion Criteria

  • Well-documented history of stroke or TIA that occurred at least 3 months prior to enrollment;
  • Age 21 years or older;
  • Continuity of care in the VAMC primary care or neurology clinics, defined as at least 1 visit in either clinic during the past 1 year;
  • On hypertensive and/or lipid-lowering agents;
  • A score of >16 on the Mini-Mental Status Exam;
  • ability to exercise (assessed by 6-minute walk or timed get up and go).

Exclusion Criteria

  • Limited life expectancy due to a severe non-CVD related comorbid terminal illness such as cancer;
  • No telephone number at which patient can be reached;
  • Plans to relocate outside of the NYC area within the next 6 months;
  • Inability to communicate over the telephone due to severe cognitive impairment or aphasia.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01122394). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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