Phase 3
Completed N=80
Efficacy of Fibrin Sealant to Reduce the Amount of Post-thyroidectomy Drain
Source: ClinicalTrials.gov NCT01126060 ↗Enrolled (actual)
80
Serious AEs
0.0%
Results posted
Dec 2011
Primary outcomePrimary: Postoperative Drainage Amount — 93.5; 105.7 mL
Summary
Fibrin sealant has been studied to reduce post-thyroidectomy drain and hospital stay as well. However, no strong evidence from well-designed clinical trials is available. Harmonic scalpel is a ultrasonic vibrating scissors which makes it easy to cut and coagulate the tissues, thus reducing op time and postoperative drain, which is important to minimize hospital stay. The investigators hypothesized that fibrin sealant combined with harmonic scalpel-assisted procedure could guarantee no-drain postoperative care in total thyroidectomy with anterior compartment neck dissection.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Postoperative Drainage Amount |
93.5; 105.7 | — |
Eligibility Criteria
Inclusion Criteria
- proven thyroid carcinoma
- Thyroidectomy with anterior compartment neck dissection
Exclusion Criteria
- No use of harmonic scalpel during surgery
- coagulation abnormality
- refuse to participate
Data sourced from ClinicalTrials.gov (NCT01126060). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.