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Home › Conditions › Thyroidectomy

Thyroidectomy

2 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Thyroidectomy

6 trials tracked for Thyroidectomy: 3 in phase 3 or 4 and 1 with published results. The most-cited published study has 44 citations.

6Trials tracked
3Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 3 3 Phase 2 1 Other / NA 2
  1. Phase 3 Superficial, Cervical Block in Thyroid Surgery, a Randomized Controlled Trial Completed · 44 cited
  2. Phase 3 Preoperative Single-dose Steroid Application for the Treatment of Nausea and Vomiting After Thyroid Surgery Completed
  3. Phase 3 Efficacy of Fibrin Sealant to Reduce the Amount of Post-thyroidectomy Drain Completed
  4. Phase 2 Identification of Nerves Using Fluorescein Sodium Completed
  5. N/A Comparison Between the Axillary Bilateral-breast Approach (ABBA) and Bilateral Axillo-breast Approach (BABA) for Robotic Thyroidectomy Completed
  6. N/A Opioid Use After Thyroid and Parathyroid Surgeries Completed

Showing the 6 most-cited and recently-updated of 6 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

What the trials found Updated — new results For clinicians

Thyroidectomy: what the trials found

The use of dexamethasone significantly reduces the incidence of postoperative nausea and vomiting (PONV) following thyroidectomy procedures 3. However, its administration does not result in a statistically significant difference in pain scores after physical stress or in the total length of hospital stay 3.

Bilateral superficial cervical blocks have been shown to reduce patient-reported pain scores as measured by the Visual Analogue Scale (VAS) 2. Despite this reduction in perceived pain, the use of these blocks did not result in a statistically significant difference in the amount or mean consumption of postoperative analgesics 2.

Fibrin sealants have been utilized in thyroidectomy procedures 4.

Recent results — preliminary, needs further review

  • Fluorescein Sodium demonstrated a ratio of nerve fluorescence compared to background tissue of 2.5 1.

For the clinician treating this condition

  • Dexamethasone is an effective intervention for reducing the incidence of postoperative nausea and vomiting, though it does not impact recovery time or pain during physical stress 3.
  • Bilateral superficial cervical blocks may improve patient comfort by lowering VAS scores, but they do not appear to reduce the overall quantity of post-operative analgesics required 2.

AI synthesis of 4 cited trials, updated Jun 22, 2026. Informational only — not medical advice; trial data sourced from ClinicalTrials.gov. How we use AI.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Early Scar Therapies After Thyroidectomy Show Modest Benefit
Orthopedics & Sports Medicine Meta-analysis
Early Scar Therapies After Thyroidectomy Show Modest Benefit Early laser and steroid treatments improve thyroidectomy scars
Early laser plus steroid or light-based protocols modestly improve neck scars after thyroidectomy, but evidence certainty is low.
Early laser plus steroid or light-based therapy may improve neck scars after thyroid surgery, but evidence is low certainty.
Frontiers Sep 8, 2026
Post-thyroidectomy rehabilitation exercise improves swallowing QoL but increases early pain in single-center RCT
Diabetes & Endocrinology RCT
Post-thyroidectomy rehabilitation exercise improves swallowing QoL but increases early pain in single-center RCT Can simple neck exercises help people swallow better after thyroid surgery?
A single-center, open-label RCT of 356 post-thyroidectomy patients without definite nerve injury found that 3 months of standardized neck an…
Simple neck exercises helped people swallow better and enjoy food sooner after thyroid surgery, with benefits lasting six months despite ear…
Apr 4, 2026