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Phase 3 Completed N=899 Randomized Quadruple-blind Treatment

Study of 0417 Ointment in the Treatment of Atopic Dermatitis

Source: ClinicalTrials.gov NCT01139450 ↗
Enrolled (actual)
899
Serious AEs
0.2%
Results posted
Sep 2014
Primary outcomePrimary: Incidence of Success Based on the Investigator's Global Evaluation at the End of Treatment — 123; 130; 86 participants

Summary

The aim of this trial is to assess the efficacy of 0417 Ointment in the Treatment of Atopic Dermatitis. Treatment medication will be administered as follows: Apply a thin layer of ointment to affected skin areas twice daily and rub in gently and completely. Study medication will be applied twice a day, approximately 12 hours apart, for approximately 4 weeks.

Outcome Measures

OutcomeResultp-value
PRIMARY
Incidence of Success Based on the Investigator's Global Evaluation at the End of Treatment
123; 130; 86
SECONDARY
The Mean Change From Baseline in the Total Individual Clinical Signs and Symptoms Per Body Region
SECONDARY
The Mean Change From Baseline in Pruritus
SECONDARY
The Mean Change From Baseline in the Percentage Total Body Surface Affected (%BSA)

Eligibility Criteria

Inclusion Criteria

  • Clinical diagnosis of Atopic Dermatitis
  • Good health with the exception of Atopic Dermatitis
  • Percent Body Surface Area minimum requirements

Exclusion Criteria

  • Subjects who are pregnant, nursing, or planning a pregnancy within the study participation period.
  • Subjects who have any systemic or dermatological disorders with the exception of Atopic Dermatitis
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01139450). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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