N/A
N=59
Exercise and Cognitive Training in Parkinson's Disease
Parkinson's Disease
Bottom Line
View on ClinicalTrials.gov: NCT01156714 ↗Enrolled (actual)
59
Serious AEs
1.7%
Results posted
Mar 2019
Primary outcome: Primary: Dual Task Function #1 — 1.15; 1.12; .987; 1.068 seconds
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Treadmill training with aerobic exercise (Behavioral); Memory training with computerized memory program (Behavioral); Combination of treadmill training and computerized memory (Behavioral)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- VA Office of Research and Development
- Primary completion
- Feb 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Dual Task Function #1 |
1.15; 1.12; .987; 1.068; 1.09; .951 | — |
| PRIMARY Dual Task Function #2 |
131.194; 116.944; 165.165; 134.7; 127.353; 174.581 | — |
| PRIMARY Cognitive Function #1 |
89.3535; 93.413; 101.236; 105.677; 103.4767; 119.6465 | — |
| PRIMARY Cognitive Function #2 |
48.37; 41.74; 48.4; 48.9; 47.8; 47.941 | — |
| PRIMARY Timed Instrumental Activities of Daily Living (TIADL) Function #1 |
0.131; .234; -.2435; 0.075; .1928; -.34 | — |
| PRIMARY Timed Instrumental Activities of Daily Living (TIADL) Function #2 |
7.339; 6.01; 3.213; 3.493; 4.746; 2.39 | — |
Summary
This study compares the effects treadmill exercise, computerized cognitive training, or the combination of the two on executive function, dual-task performance, and performance on several Instrumental Activities of Daily Living (IADLs).
Eligibility Criteria
Inclusion Criteria
- Parkinson's disease stage 1-3 Hoehn and Yahr
- Balance problems
Exclusion Criteria
- unstable medical illness
- unstable psychiatric illness
- exercising too much on own
- doing computerized memory training on own
Data sourced from ClinicalTrials.gov (NCT01156714). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.