Meta-analysis shows MRI volumetric differences in Parkinson's disease with mild cognitive impairment versus cognitively normal patients
New scan signs reveal early brain changes in Parkinson's dementia risk
This systematic review and meta-analysis evaluates gray matter volume alterations across six subcortical regions in patients with Parkinson'…
A new scan pattern shows specific brain shrinkage in Parkinson's patients who are starting to forget things, helping doctors catch dementia …
Review of LLM-generated synthetic Parkinson's patients for in silico trials
AI creates synthetic patients to help Parkinson's trials work better
This review synthesizes a methodological proof-of-concept on generating synthetic Parkinson's disease patients using a large language model.…
New AI technology creates virtual patients to help test Parkinson's drugs without breaking privacy rules during clinical research.
Psychomotor retardation in depression linked to increased Parkinson's risk
Slowed movement in depression signals higher Parkinson disease risk
A retrospective cohort study of 6327 individuals with depression found that those with psychomotor retardation had a 43% higher risk of deve…
Depression with slowed movement links to future Parkinson risk, suggesting physical signs may warn of brain changes years before diagnosis.
Narrative review highlights association between abnormal bilirubin and Parkinson's disease motor outcomes
Bilirubin’s Hidden Role in Slowing Parkinson’s Progress
This narrative review examines the relationship between abnormal bilirubin levels and Parkinson's disease in patients. Authors report that t…
A common substance in your blood—usually linked to jaundice—might actually shield the brain in Parkinson’s disease, changing how doctors cou…
Auditory targeted memory reactivation during NREM sleep nap shows no effect on motor retention
Sleep sounds changed brain waves but did not fix motor memory in Parkinson's
This study investigated the effects of auditory targeted memory reactivation (TMR) during a 2-hour NREM sleep nap on motor sequence learning…
New sleep sounds changed brain waves but did not improve movement memory in Parkinson's patients, showing a gap between brain activity and r…
CSF SAA status associates with levodopa responsiveness and motor progression in Parkinson's disease patients.
Parkinson’s test predicts levodopa response and motor decline speed
This observational cohort study analyzed 223 sporadic Parkinson's disease participants from the PPMI cohort initiating levodopa. SAA+ patien…
Test reveals Parkinson’s patients with alpha-synuclein seeds respond better to levodopa and decline slower than those without the seeds.
Baduanjin training improves motor symptoms and anxiety more than brisk walking in Parkinson's disease
Mindful movement training improved motor skills and mood better than brisk walking for early Parkinson's.
A 12-week randomized controlled trial in 32 patients with early- to mid-stage Parkinson's disease found that Baduanjin training led to signi…
In patients with early Parkinson's, a gentle, mindful exercise program boosted movement and mood more than brisk walking after three months.
Narrative review examines resveratrol in Alzheimer's, Parkinson's, MS, and cerebral ischemia with noted limitations.
This Common Food Compound May Shield Your Brain From Damage
This narrative review evaluates resveratrol across Alzheimer's disease, Parkinson's disease, multiple sclerosis, and cerebral ischemia. The …
A natural compound found in berries shows promise for protecting brain cells, but human proof is still missing.
Review of music therapy for motor, speech, and cognitive impairments in stroke, Parkinson's, and cerebral palsy
Music therapy may help improve motor, speech, and cognitive function in neurological conditions.
This narrative review examines the role of music therapy for patients with stroke, Parkinson's disease, or cerebral palsy. The authors synth…
A review suggests music therapy might improve motor, speech, and cognitive impairments for people with stroke, Parkinson's disease, or cereb…
FDA Approves DATSCAN (ioflupane I-123) for Striatal Dopamine Transporter Visualization in Suspected Parkinsonian Syndromes or Dementia with Lewy Bodies
FDA approves new brain imaging drug to help doctors diagnose Parkinson's and similar conditions.
DATSCAN is approved as an adjunct diagnostic for striatal dopamine transporter visualization using SPECT brain imaging in adult patients wit…
FDA approves new brain imaging drug to help doctors diagnose Parkinson's and similar conditions.
Systematic review and meta-analysis of oxidative stress biomarkers in older adults with T2DM or Parkinson's disease
Parkinson’s and Diabetes Linked by Hidden Body Damage
This systematic review and meta-analysis evaluated oxidative stress biomarkers in serum, plasma, or leukocytes from 7,521 human subjects age…
Two common diseases may fuel each other through invisible cell damage, making care harder for millions living with both Parkinson's and type…
Observational review of phenoconversion rates and biomarker alignment in Parkinson's disease genetic cohorts
Do your symptoms match the biology, or is the disease hiding in plain sight?
This observational cohort analysis reviews phenoconversion rates and biomarker alignment in Parkinson's Progression Markers Initiative parti…
In people at genetic risk for Parkinson's, symptoms and biological markers often don't align, with nearly one-third showing advanced brain c…