Phase 3
N=130
Vitamin D in Vulnerable Adults (VIVA-VA)
Frail Elderly · Vitamin d Deficiency
Bottom Line
View on ClinicalTrials.gov: NCT01170273 ↗Enrolled (actual)
130
Serious AEs
5.4%
Results posted
Dec 2016
Primary outcome: Primary: Change in Short Physical Performance Battery Test Score — 7.3; 7.0 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 3
- Interventions
- vitamin D (Dietary_supplement); placebo (Dietary_supplement)
- Age
- Older Adult · 65+ yrs
- Sex
- Male
- Sponsor
- VA Office of Research and Development
- Primary completion
- Jun 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Short Physical Performance Battery Test Score |
7.3; 7.0 | — |
Summary
Vitamin D insufficiency is a problem of growing concern, given its prevalence in older persons and the association of low vitamin D with multiple major health problems, including mobility and balance deterioration and falls, cardiovascular disease, diabetes, and certain cancers. Sedentary persons are particularly vulnerable for these health problems and generally not adherent to prescribed physical activity. This study will investigate if treatment with vitamin D will benefit physical performance in male veterans age 65 to 95.
Eligibility Criteria
Inclusion Criteria
- male veterans
- 65 to 95 years of age
- independent
- sedentary
- vitamin D insufficiency
Exclusion Criteria
- hypercalcemia
- renal failure
- living in a nursing home
Data sourced from ClinicalTrials.gov (NCT01170273). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.