N/A N=20 Other

Vascular Endothelium Changes After Bariatric Surgery (Endothelial Progenitor Cells)

Type 2 Diabetes

Bottom Line

View on ClinicalTrials.gov: NCT01213940 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2020

Primary outcome: Primary: Change in Late Outgrowth Endothelial Progenitor Colonies — 0.3; 0.2; 3.1; 0.1 LOEPC colonies — p=<0.05

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: pre-bariatric weight loss program (Behavioral); bariatric surgery (Procedure)
Age: Adult, Older Adult · 19+ yrs
Sex: All
Sponsor: University of South Alabama
Primary completion: May 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Late Outgrowth Endothelial Progenitor Colonies	0.3; 0.2; 3.1; 0.1	<0.05 sig

Summary

Improvement in cardiovascular mortality is related to changes in pathologic autoantibodies and in the number of circulating functional replicative competent endothelial progenitor cells (EPC's) after bariatric surgery.

Eligibility Criteria

Inclusion Criteria

Type 2 Diabetes, Glucose > 200mg/dl, currently be ing treated with oral medications and HGA1c . 6.5, and BMI .35.

Exclusion Criteria

Type 1 Diabetes

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01213940). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.