Research across Diabetes
Related studies from across the Diabetes family.
Questions about Type 2 Diabetes
What common genes link Polycystic Ovary Syndrome and type 2 diabetes according to recent studies?
Recent studies link PCOS and type 2 diabetes through shared genetic variants, notably the insulin gene VNTR and epigenetic changes in metabolism-related genes.
Full answer →What are the standard treatment options available for someone with Type 2 Diabetes?
Standard treatment for type 2 diabetes includes lifestyle changes (diet, exercise), metformin, other medications like GLP-1 agonists (e.g., semaglutide, tirzepatide), and sometimes insulin, along with monitoring blood sugar and managing cardiovascular risk.
Full answer →What are the best lifestyle changes to manage Type 2 Diabetes effectively?
A Mediterranean diet, regular physical activity, weight loss, and digital health tools can effectively manage type 2 diabetes, with medication support as needed.
Full answer →All Type 2 Diabetes Articles
- Resveratrol supplementation significantly reduces LDL-C but lacks consistent impact on glycemic indices in type 2 diabetes
- SGLT2 inhibitors associated with lower all-cause mortality in heart transplant recipients with type 2 diabetes
- Single-incision sleeve plus bypass shows short-term safety and metabolic improvement in 3 patients with obesity and T2DM
- Transcriptomic analysis identifies 337 high-confidence genes associated with Type 2 Diabetes in human pancreatic islets
- SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
- Metformin is associated with higher lactate concentrations during exercise in adults with prediabetes and type 2 diabetes
- Semaglutide reduces risk of kidney decline or death in type 2 diabetes and CKD
- Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
- GLP-1 receptor agonists may reduce cognitive decline in type 2 diabetes patients with dementia
- Evolocumab reduces cardiovascular events in diabetes without known atherosclerosis
- Long-term voglibose use likely caused leukopenia in a 71-year-old man with type 2 diabetes
- scFv-based biologics show potential for immunomodulation in type 1 and type 2 diabetes
- Insulin degludec/liraglutide ranks highest for HbA1c reduction with SUCRA value of 89.4%
- Metabolic subtypes identify Japanese adults with prediabetes at highest or lowest T2D risk
- Eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity
- 37 loci linked to gestational diabetes, 7 novel, in large multi-ancestry meta-analysis
- AI-driven cardiovascular risk prediction in type 2 diabetes shows promise but bias and lack of diversity limit clinical use
- GLP-1 receptor agonists show no increased ocular disorder risk in type 2 diabetes meta-analysis
- GLP-1RAs show lower risk of serious liver events compared with DPP-4 inhibitors in adults with type 2 diabetes
- Real-time CGM improved HbA1c versus SMBG in adults with type 2 diabetes on basal insulin and modern therapies
- Sitagliptin and liraglutide superior for CGM targets in type 2 diabetes
- Thiazolidinediones show lower hepatocellular carcinoma risk than DPP-4 inhibitors, GLP-1RAs, insulin, and sulfonylureas in this network meta-analysis
- SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
- Paternal metformin use during spermatogenesis shows no increased risk for major congenital malformations in over 11 000 children across five countries
- Resistance training reduces hemoglobin A1c by 0.62% and systolic blood pressure by 3.91 mmHg in type 2 diabetes
- Multicomponent behavioral interventions show sustained HbA1c reduction in type 2 diabetes
- Greater weight loss and supervised exercise reduce diabetes risk in adults with prediabetes
- Lifestyle programs show no significant diabetes incidence reduction in 14 studies of at-risk individuals
- Trans fatty acids from dairy foods show no increased cardiometabolic risk in systematic review and meta-analysis
- SGLT2 and dual SGLT1/2 inhibitors reduce cardiovascular death or heart failure hospitalization risk in type 2 diabetes patients
- Triple oral therapy with metformin, SGLT-2, and DPP-4 inhibitors lowers HbA1c better than dual regimens in adults with type 2 diabetes
- Natural polysaccharides enhance insulin sensitivity and protect pancreatic beta-cells in type 2 diabetes
- Probiotics, synbiotics, and berberine modestly lower fasting glucose and HbA1c in type 2 diabetes
- Women with Type 1 Diabetes have a 2.10 times higher risk of female sexual dysfunction compared to age-matched controls
- Systematic review and meta-analysis of tirzepatide effects on HbA1c and weight in adults with type 2 diabetes
- Network meta-analysis compares exercise types for glycemic control in type 2 diabetes
- Genetic analysis links GLP-1 agonism to pancreatitis risk and sarcopenia in large cohorts
- Meta-analysis identifies rare gene-trait associations across 1.2 million individuals in global biobanks
- Systematic review and meta-analysis of lifestyle interventions for Type 2 Diabetes in West Africa
- Review of lifestyle factors linked to Type 2 Diabetes risk in Qatar
- Meta-analysis finds higher intrapancreatic fat in type 2 diabetes
- CGM may boost treatment satisfaction in type 2 diabetes, but other outcomes unclear
- Narrative review proposes FISI tools for metabolic syndrome and diabetes management across the life cycle
- Case report and review of literature on acute NSTEMI after fluorescein angiography in a 76-year-old woman
- Systematic review of curcumin with piperine for metabolic and cardiometabolic conditions
- Meta-analysis of Mendelian randomization suggests GLP-1 receptor agonism lowers vascular dementia risk
- Meta-analysis: Resistance training improves vascular function in type 2 diabetes
- Review of GLP-1RAs in Type 2 Diabetes and Atherosclerosis Mechanisms
- Meta-analysis of blood pressure levels and outcomes in type 2 diabetes participants
- Systematic review and meta-analysis on VR for Type 2 Diabetes management
- Pediatric Gut Microbiome Links to Metabolic Dysfunction-Associated Steatotic Liver Disease and Type 2 Diabetes
- Network meta-analysis compares bexagliflozin efficacy and safety with other SGLT2 inhibitors in type 2 diabetes
- Systematic review and meta-analysis of HIIT versus MICT for Type 2 Diabetes outcomes
- Meta-analysis of GWAS in Native Hawaiians and Polynesians identifies 25 trait loci for diabetes and obesity traits
- Systematic review of 88 observational studies on missing data reporting in T2DM-MCI research
- Meta-analysis finds Type 2 diabetes linked to poorer survival in solid tumor patients on immune checkpoint inhibitors
- Network meta-analysis compares glucose-lowering therapies for heart failure with reduced ejection fraction and type 2 diabetes
- Systematic Review and Meta-Analysis of Subcutaneous CGM in Elective Surgery
- Systematic review of saponins for type 2 diabetes and its complications
- Digital Health Interventions Show Mixed Results for Cardiovascular Risk Reduction in Type 2 Diabetes Patients Across Weight Categories
- Tirzepatide improves standard and intensive therapeutic target attainment versus semaglutide in adults with type 2 diabetes
- Personalized diabetes texting with peer support improved glycemic control and remission rates in type 2 diabetes patients
- Afternoon/Evening Exercise May Lower Blood Pressure More Than Morning Exercise: Meta-Analysis
- Systematic review and meta-analysis links Mediterranean diet to improved cardiometabolic markers
- Text messaging plus educational materials improves healthy eating in uncontrolled diabetes
- Systematic review and meta-analysis links Type 2 Diabetes to higher fracture risk across multiple anatomical sites
- Fasting plasma glucose shows higher diagnostic accuracy than HbA1c for undiagnosed diabetes in adults
- Review of NHANES data links metformin use to lower mortality and inflammatory markers in type 2 diabetes
- A 1-month nudge-based dietary intervention increased daily step counts by 1105 steps at 3 months in adults with type 2 diabetes
- Mobile app plus group sessions showed feasibility in Malaysian women with gestational diabetes
- Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
- Essential phospholipids reduced hepatic steatosis and improved HbA1c in patients with MASLD and type 2 diabetes over 6 months
- Reversion of Prediabetes to Normoglycemia Linked to 68% Lower Diabetes Risk
- Ecnoglutide Reduces HbA1c and Body Weight in Type 2 Diabetes: Meta-Analysis
- Meta-analysis finds GLP-1RA plus SGLT2i reduces UACR in type 2 diabetes with kidney disease
- Systematic review and meta-analysis of hypoglycaemia risk prediction models in type 2 diabetes
- GLP-1RAs reduce weight and HbA1c in severe mental illness with low discontinuation rates
- Narrative review discusses pharmacological and lifestyle interventions for type 2 diabetes and psychological health
- Guideline narrative review discusses diabetes risks from immunosuppressive therapy in kidney transplant recipients
- Baseline anti-GIP antibody levels associate with future diabetes-range glycemia in health checkup cohort
- Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
- Review of miRNA associations with high-risk diabetes profiles in midlife women
- Baseline vitamin D levels linked to semaglutide glycemic and weight outcomes in type 2 diabetes
- GenMetS polygenic score association with cardiometabolic risk in Asian populations
- Semaglutide high dose for weight reduction in people with Type 2 Diabetes
- Individual-participant data meta-analysis shows blood-pressure lowering reduces cardiovascular risk in CKD and non-CKD populations
- Machine learning model improves early detection of occult diabetic kidney disease in hospitalized patients
- High LDL-C to HDL-C ratio linked to cardiovascular events in type 2 diabetes with retinopathy
- Observational study suggests multi-omic scores improve Type 2 Diabetes risk assessment in UK Biobank and MESA cohorts
- Meta-analysis suggests Hatha yoga may improve blood pressure and glucose in non-communicable disease patients
- Telemedicine applications in general practice show positive clinical outcomes for chronic diseases
- Metformin use in Type 2 Diabetes shows inconsistent clinical effects in review
- Combination valsartan and dapagliflozin improves blood pressure and glucose in Type 2 Diabetes and hypertension
- Narrative review links microgravity exposure to altered fat distribution and inflammation in metabolic disease models
- Meta-analysis of dapagliflozin for renal outcomes in type 2 diabetes and CKD
- Semaglutide linked to lower neuropsychiatric event risk vs other diabetes drugs in observational study
- Observational review of layered data models improves DKD risk detection in type 2 diabetes cohorts
- Higher ZJU index associated with worse metabolic profiles in adults with type 2 diabetes and hyperuricemia
- Observational Study Evaluating Hospital-Based Chronic Disease Management Platform in Adults With Type 2 Diabetes
- Meta-analysis links genetic variants to gestational diabetes mellitus risk in British, Finnish, and Chinese populations
- Meta-analysis of sex differences in insulin therapy outcomes for adults with Type 1 and Type 2 diabetes
- Scoping review on AI fundus photography for Type 2 Diabetes highlights limited external validation and calibration
- Higher Geriatric Nutritional Risk Index linked to lower osteoporosis risk in diabetic women
- Salivary growth factors differ in type 2 diabetes after tooth extraction
- Systematic review suggests resveratrol may improve glycemic control and protect pancreatic beta-cell function in diabetes
- Retinal microvascular features associated with subclinical cardiovascular dysfunction in type 2 diabetes
- Antiresorptive and Anabolic Agents Improve Bone Microarchitecture in Postmenopausal Women With Type 2 Diabetes: Pilot RCT
- Non-traditional lipid indices associate with coronary heart disease risk in MASLD and type 2 diabetes patients
- Narrative review compares tirzepatide and semaglutide for obesity and type 2 diabetes outcomes
- TyG-WC and TyG-WHtR indices associated with liver-related events in type 2 diabetes
- FluxPro-DKD fusion model integration shows higher AUC for early-stage DKD detection in type 2 diabetes
- Tirzepatide MTD Demonstrates Cost-Effectiveness Versus Semaglutide MTD in Obesity Simulation Modeling Study
- Untargeted LC-MS/MS profiling identifies metabolite networks associated with glycemic dysregulation in diabetes cohorts
- IGFBP2 as a context-dependent regulator of metabolic dysregulation in obesity and type 2 diabetes
- Retrospective cohort study assesses diagnostic accuracy for Wagner Grade ≥2 DFUs in hospitalized type 2 diabetes patients
- Laboratory study examines SLC30A8 R138X variant effects on human stem cell-derived islet-like clusters
- Review of new-user target trial emulation comparing semaglutide and SGLT2i in U.S. Veterans with type 2 diabetes
- Systematic review and meta-analysis of oxidative stress biomarkers in older adults with T2DM or Parkinson's disease
- Genetic analyses suggest causal links between type 2 diabetes markers and cerebral small vessel disease phenotypes
- Literature review synthesizes Schisandra chinensis effects on gut microbiota and metabolic pathways across multiple conditions
- Meta-analysis of Gynostemma pentaphyllum for glycemic control in diabetes patients
- Observational biobank study compares phenomic and social determinants for disease risk prediction
- Retrospective cohort finds COVID-19 infection linked to proteinuria progression in type 2 diabetes
- Monitoring report on US GLP-1 RA prescribing trends shows increased oral semaglutide use
- Young-onset type 2 diabetes and menopause status linked to all-cause mortality in Chinese women
- SBSPON gene variant rs2291219 linked to higher T2DM risk in Northwest Indian population
- Three-parameter online nomogram predicts diabetic retinopathy risk in community-dwelling type 2 diabetes patients
- Inflammatory and metabolic indices associated with microvascular complications in hospitalized type 2 diabetes patients
- Tirzepatide shows greater lean body mass loss than semaglutide in first-episode GLP-1RA users with type 2 diabetes
- Cross-Sectional Analysis of Protective Foot Sensation and Complications in 387 Type 2 Diabetes Patients
- Bioinformatics study identifies shared immune genes and potential drugs for PCOS and T2DM
- Mazdutide monotherapy reduces HbA1c and promotes weight loss in Chinese adults with type 2 diabetes over 48 weeks
- Systematic review and meta-analysis of Mendelian randomization studies examining T2DM and cancer associations
- Multidisciplinary management in T2DM patients yielded a 29.24% remission rate in a single-arm observational study
- Bayesian network meta-analysis evaluates antidiabetic medications and dementia risk in 4,382,897 patients
- Preprint paired analysis suggests VSG may improve metabolic and renal markers in youth with T2D and obesity
- Mini-review links insulin to worse COVID-19 outcomes in type 2 diabetes patients
- GLP-1RA use shows sex-specific pancreatitis and hypotension risks in T2D second-line therapy study
- In older in-patients with type 2 diabetes and cognitive impairment, CGM showed superior glucose metrics compared to point-of-care tests
- GLP1R locus variants associated with higher BMI and Type 2 Diabetes risk in genetically inferred European ancestry participants
- MTHFR C677T polymorphism linked to elevated risk of schizophrenia and type 2 diabetes comorbidity in Han Chinese patients
- Feijoa powder supplementation did not improve weight or glucose but lowered systolic blood pressure in adults with prediabetes
- Single-dose fultagliptin benzoate pharmacokinetics and safety in patients with mild to moderate renal insufficiency versus healthy volunteers
- PIEZO1 variant rs563555492T associated with lower HbA1c and reduced prediabetes risk in South Asian cohorts
- Single aerobic exercise bout shows mixed effects on glucose and neuronal insulin signaling in obesity
- Circulating spexin levels are significantly lower in patients with type 2 diabetes mellitus compared to controls
- Orforglipron shows superior HbA1c reduction versus oral semaglutide in adults with type 2 diabetes on metformin
- HALP score and clinical parameters predict time to glycemic stability in hospitalized type 2 diabetes patients
- Meta-analysis identifies risk factors for diabetic kidney disease in Asian patients with type 2 diabetes
- Meta-analysis finds high prevalence of adverse outcomes in African women with hyperglycaemia in pregnancy
- Post-hoc analysis finds both continuous and intermittent calorie restriction reduce weight in type 2 diabetes
- Intraduodenal Lauric Acid and Tryptophan Reduce Postprandial Glucose in Small Diabetes Trial
- Dairy-inclusive diet with timed meals may improve circadian gene expression and glycaemia in type 2 diabetes
- Biological age acceleration transitions associated with higher type 2 diabetes and mortality risk in UK Biobank cohort
- Higher dietary phytochemical index associated with better sleep quality in adults with type 2 diabetes
- Systematic review shows PCOS in obese women links to high MASLD and 2–4 fold increased cardiovascular and diabetes risks
- Protocol compares Mediterranean and low-carb diets for diabetes remission in Lebanese adults
- Elevated peripheral HIF-1α levels associated with higher fasting glucose and HbA1c in patients with type 2 diabetes mellitus
- QingYun7 dietary intervention improves glycemic control in patients with type 2 diabetes
- Low-load blood-flow restriction training improves mitochondrial capacity and fat loss in type 2 diabetes compared to conventional resistance training
- Technology-based interventions showed greater weight loss in women with prior gestational diabetes compared to control groups
- Network meta-analysis of novel antidiabetic drugs in T2DM with CKD shows sotagliflozin, empagliflozin, and semaglutide rank highest for cardiovascular and renal outcomes
- Network meta-analysis finds acupuncture therapies may improve glycemic parameters in type 2 diabetes
- Oral semaglutide reduces composite heart failure outcomes in patients with type 2 diabetes and heart failure history
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Type 2 Diabetes and Heart Failure Risk Reduction
- FDA Approves Dapagliflozin and Metformin Hydrochloride Extended-Release Tablets for Type 2 Diabetes and Related Risks
- Pressure-controlled volume-guaranteed ventilation improved diaphragmatic function and reduced weakness in diabetic patients undergoing laparoscopic colorectal surgery
- Anal fistula incidence higher in diabetic patients; current management strategies may be suboptimal
- FDA Approves Dapagliflozin Tablets (dapagliflozin) to Reduce Heart Failure Hospitalization Risk and Improve Glycemic Control in Adults with Type 2 Diabetes
- FDA Approves Dapagliflozin for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin for Reducing Heart Failure Hospitalization Risk and Improving Glycemic Control in Adults with Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Type 2 Diabetes and Heart Failure Risk Reduction
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) for Heart Failure Risk Reduction and Glycemic Control in Type 2 Diabetes
- FDA Approves Dapagliflozin Tablets (dapagliflozin) to Reduce Heart Failure Hospitalization Risk in Adults with Type 2 Diabetes
- Elevated plasma phenylalanine associated with obesity, type 2 diabetes, and cancer risk
- Ticagrelor Not Noninferior to Prasugrel in Diabetes Patients With Multivessel CAD After PCI
- Urinary podocin and nephrin show poor short-term prediction of DKD progression in type 2 diabetes
- Finerenone linked to improved KDIGO risk categories in T2D and CKD patients
- PPARα rs6008845 genotype modifies fenofibrate benefit for vascular events in type 2 diabetes
- Resistance and interval training plus berry extract did not alter muscle AGEs in older adults
- GLP-1 receptor agonists associated with lower respiratory sequelae risk in case report analysis
- Tadalafil reduces some plasma neurodegeneration biomarkers in type 2 diabetes patients
- BP variability and pulse pressure associated with cognitive decline in type 2 diabetes patients
- Posterior slab cast shows higher healing rate than total contact cast for diabetic foot ulcers in single-center RCT
- Oral quadruple therapy reduces HbA more than metformin uptitration in type 2 diabetes on triple therapy
- Subgroup analysis finds tirzepatide superior to dulaglutide for HbA1c and weight in type 2 diabetes
- GLP-1RAs reduce MACE risk in Asian and White adults with diabetes or overweight
- Hepatic insulin resistance linked to greater central obesity in Korean adults with type 2 diabetes
- Exercise therapy shows benefits for type 2 diabetes management, but adherence challenges persist
- New-onset diabetes in adults over 50 associated with higher pancreatic cancer risk within 3 years
- Gluteus maximus morphology shows sex-specific associations with type 2 diabetes risk in UK Biobank imaging
- Plant bioactive polysaccharides show metabolic benefits in umbrella review of systematic reviews
- AI-ready dataset created for type 2 diabetes research, lacking clinical validation
- Self-management and glycemic control linked to lower MCI risk in rural elderly with type 2 diabetes
- LCHF and HCLF diets both improve HRQoL in type 2 diabetes, with no significant between-group difference
- Polypharmacy and age predict MACE in rural Montana type 2 diabetes cohort
- Vildagliptin reduces specific TG species in T2D; GLP-1 blockade increases total TGs
- Youth diabetes incidence increased from 2002-2015, with higher rates of increase in minority populations