Research across Diabetes
Related studies from across the Diabetes family.
Questions about Type 2 Diabetes
Do GLP-1RAs help improve walking distance for those with diabetes and Peripheral Artery Disease?
Yes, GLP-1 receptor agonists (liraglutide, semaglutide) improve walking distance in people with type 2 diabetes and peripheral artery disease, based on a 2025 meta-analysis of randomized trials.
Full answer →What common genes link Polycystic Ovary Syndrome and type 2 diabetes according to recent studies?
Recent studies link PCOS and type 2 diabetes through shared genetic variants, notably the insulin gene VNTR and epigenetic changes in metabolism-related genes.
Full answer →What are the standard treatment options available for someone with Type 2 Diabetes?
Standard treatment for type 2 diabetes includes lifestyle changes (diet, exercise), metformin, other medications like GLP-1 agonists (e.g., semaglutide, tirzepatide), and sometimes insulin, along with monitoring blood sugar and managing cardiovascular risk.
Full answer →What are the best lifestyle changes to manage Type 2 Diabetes effectively?
A Mediterranean diet, regular physical activity, weight loss, and digital health tools can effectively manage type 2 diabetes, with medication support as needed.
Full answer →All Type 2 Diabetes Articles
- Systemic shifts toward lifelong cardiometabolic prevention address gaps in managing cardiovascular disease and type 2 diabetes
- Antidiabetic drugs and gut microbiota interact to influence treatment efficacy and tolerability in metabolic syndrome
- Butyrate and fecal acetate levels are significantly lower in patients with type 2 diabetes
- Laparoscopic excision of a hypervascular mass confirms hyaline vascular-type unicentric Castleman disease in a patient with diabetes
- Short-bout accumulated physical activity reduces mean glucose in adults with type 2 diabetes
- Older age, longer diabetes duration, and higher HbA1c levels associate with sarcopenia in type 2 diabetes
- Ecnoglutide improves glycemic control and reduces body weight in adults with type 2 diabetes
- OSA Tied to Poorer Glucose Control in Type 2 Diabetes
- Survodutide Improves Beta Cell Function and Insulin Sensitivity in T2D and Obesity
- Comparative Efficacy of GLP-1 Receptor Agonists for Adolescent Obesity and Type 2 Diabetes
- CareAide mHealth application improves medication adherence and quality of life in type 2 diabetes
- Exercise interventions improve metabolic flux and fatty acid oxidation in Type 2 Diabetes
- SGLT2 inhibitors not tied to gastrointestinal cancer risk in type 2 diabetes meta-analysis
- Thiazolidinediones increase bladder cancer risk while SGLT2 inhibitors show potential protective effects in Type 2 Diabetes
- Evaluating Glycemic Control and Weight Reduction of SGLT2 Inhibitors Versus DPP-4 Inhibitors
- Higher Triglyceride-glucose index is associated with increased risk of diabetic peripheral neuropathy
- NT-proBNP and cTnI as Prognostic Biomarkers in Type 2 Diabetes Patients
- Alert-based CDS increases UACR testing from 11.5% to 36.0% in patients with type 2 diabetes
- GLP-1 receptor agonists reduce MACE (HR 0.69) and all-cause mortality (HR 0.67) in Type 2 Diabetes
- Early time-restricted eating and bright light therapy protocol for insulin-independent type 2 diabetes
- Tirzepatide reduces MACE in adults with Type 2 Diabetes and obesity (OR 0.87)
- Low fat-free mass metrics are associated with increased risk of weight-related metabolic complications
- High-risk adiposity and inflammation trajectories correlate with significantly increased risk of incident Type 2 Diabetes
- Lithium-associated nephrogenic diabetes insipidus may cause severe postoperative hypernatremia and polyuria
- Magnesium oxide results in modest, non-significant HbA1c reduction in Type 2 Diabetes
- Combined aerobic-resistance training provides superior metabolic benefits for obese patients with type 2 diabetes
- Continuous ancestry representation boosts power in multi-ancestry meta-analysis for type 2 diabetes
- Elastic-band resistance training improves HbA1c and fasting plasma glucose in adults with type 2 diabetes
- Discharge planning for diabetes is multicomponent but lacks consistent outcomes and long-term follow-up
- Allostatic load serves as a predictor of surgical outcomes and explains socioeconomic disparities
- Pharmacist-led medication therapy management improves adherence and glycemic control in a patient with complex T2DM
- Pharmacist-integrated collaborative outpatient care reduces systolic blood pressure by 7.11 mm Hg in CKM populations
- Medically tailored groceries reduce HbA1c by 0.40 points in Medicaid-insured adults with type 2 diabetes
- Tirzepatide reduces hypertension risk but increases hypotension risk compared to semaglutide in T2DM and obesity
- Evaluation of Once Weekly Subcutaneous Zenagamtide for Management of Type 2 Diabetes
- Poor glycemic control in Type 2 Diabetes is associated with lower FEV1 and FVC volumes
- Structured education programs reduce HbA1c and multiple cardiometabolic risk factors in Type 2 Diabetes
- Glucagon-like peptide-1 receptor agonists associated with reduced Parkinson's disease risk in type 2 diabetes
- SGLT2 inhibitors raise hematocrit by 2.29% and hemoglobin by 0.51 g/dL in type 2 diabetes
- Tirzepatide reduces inflammatory markers and improves metabolic biomarkers in patients with obesity
- Psoriasis patients with moderate to severe disease show higher prevalence of type 2 diabetes
- BCAA metabolism modulation may improve insulin sensitivity and alleviate metabolic inflammation in Type 2 Diabetes
- 4-year lifestyle intervention cuts type 2 diabetes risk by 46% in post-GDM women
- Polypharmacy and insulin therapy significantly increase hypoglycemia odds in adults with type 2 diabetes
- Multidimensional CHW intervention reduces HbA1c by 1.0 percentage points in patients with type 2 diabetes
- Park visits and moderate-to-vigorous physical activity are associated with lower depressive symptoms
- COPD patients have higher odds of diabetes mellitus with an adjusted OR of 1.39
- SGLT2 inhibitors significantly reduce dementia risk in patients with type 2 diabetes
- Steviol glycosides serve as sucrose substitutes, but metabolic benefits need human validation
- GLP-1 receptor agonists associated with favorable cardiovascular outcomes in adults with Type 2 Diabetes
- Contextual adaptation and multi-level factors influence translation of dietary interventions for type 2 diabetes
- Time-restricted eating reduces body weight, BMI, and HbA1c in adults with type 2 diabetes
- Digital wearables support exercise self-management in type 2 diabetes via six behavior pathways
- AML infiltration of bile duct identified as primary cause of acute pancreatitis in case report
- Undiagnosed Type 2 Diabetes prevalence of 6.67% among adults in South Asia
- Face-to-face DSME produces approximately 1.3% HbA1c reduction at 30 weeks in type 2 diabetes
- High-intensity interval training associated with -0.73% HbA1c reduction in adults with type 2 diabetes
- Culturally tailored self-management interventions significantly decrease HbA1c levels in people with type 2 diabetes
- GLP-1 RA exposure in early pregnancy not significantly tied to hypertensive disorders
- mHealth apps reduce HbA1c by 0.39% in type 2 diabetes across 19 RCTs
- Oral-health promotion improves outcomes for adults with type 2 diabetes when guidance is provided
- OSAS not significantly tied to diabetic retinopathy overall, but risk doubles in Asian subgroups
- Proposed pathway for systematic MASLD/MASH assessment in type 2 diabetes
- Four specific miRNAs in extracellular vesicles satisfy high-tier causality for metabolic and inflammatory regulation
- Metabolic surgery review outlines framework for T2DM and obesity management
- SGLT2 inhibitors and GLP-1 receptor agonists show similar MACE reduction in type 2 diabetes
- SGLT2 inhibitors reduce body fat without significant impacts on skeletal muscle mass in type 2 diabetes
- Incretin-based weight loss lower in type 2 diabetes trials, but confounded by demographics
- Insulin resistance and hyperinsulinemia drive bidirectional links between biological aging and age-related chronic diseases
- Vitamin D deficiency is prevalent among African patients with Type 2 Diabetes and higher HbA1c
- GLP-1 receptor agonists and tirzepatide provide cardiovascular benefits across multiple clinical scenarios
- GLP-1 Receptor Agonists Associated with Reduced Cancer Risk in Patients with Type 2 Diabetes
- Specific gut microbiota taxa are associated with the presence of diabetic retinopathy in T2DM patients
- Bibliometric Analysis Mapping the Evolution of Stem Cell Therapies for Diabetes Management
- Exercise ameliorates both type 1 and type 2 diabetes through multiple mechanisms
- Liraglutide reduces stroke recurrence from 18.1% to 5.8% in patients with high insulin resistance
- Dapagliflozin plus pioglitazone reduces HbA1c by 0.49% and improves liver fat content in T2DM
- Unified cardiometabolic disease framework links T2DM, ASCVD, HFpEF, MASLD, hypertension, and CKD via shared pathophysiology
- GQD plus metformin significantly reduces FPG and 2hPG in adults with Type 2 Diabetes
- Mediterranean and DASH diets consistently support mitigation of cardiometabolic risk in metabolic syndrome patients
- Orforglipron Demonstrates Superior Glycaemic Control Over Dapagliflozin in Type 2 Diabetes
- Tirzepatide Efficacy and Safety for Managing Type 2 Diabetes in Chinese Patients
- AI models demonstrate high accuracy in predicting progression from Gestational Diabetes to Type 2 Diabetes
- Prediction models demonstrate high accuracy for identifying progression from prediabetes to Type 2 Diabetes Mellitus
- Cagrilintide-semaglutide reduces HbA1c by up to 2.33% in adults with type 2 diabetes
- Ubiquitination modifications by E3 ligases and DUBs form tissue-specific regulatory networks in Type 2 Diabetes
- Oral small-molecule GLP-1RAs reduce body weight by 3.93 and HbA1c by 0.94
- Patients with cardiovascular diseases show measurable prevalence of active cancer across multiple conditions
- Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
- Gut microbiota may influence metabolic response to GLP-1 receptor agonists in obesity and type 2 diabetes
- Two-year exercise training improves bone mineral density and trabecular bone score in type 2 diabetes
- Metabolic Dysfunction-Associated Steatotic Liver Disease prevalence reaches 56.9% among diabetic adults in India
- Mobile-ecological momentary assessment shows 70% compliance rate among adolescents and young adults with diabetes
- Canagliflozin mitigates increased cardiovascular risk from low-normal sodium intake in type 2 diabetes and CKD
- Metabolic and bariatric surgery achieves 70% steatohepatitis remission in patients with MAFLD
- Combined FGF-21 and GDF-15 show high diagnostic accuracy for insulin resistance in type 2 diabetes
- Pooled prevalence of diabetic kidney disease among Brazilian adults is 27.06% across 46 studies
- Initial dual oral therapy improves HbA1c target achievement in early stage type 2 diabetes
- CHGZGJT combined with conventional treatment improves HbA1c, fasting glucose, and lipid profiles in Type 2 Diabetes
- Finerenone reduces mortality and heart failure risk (HR 0.644) in post-AMI patients
- Combined exercise interventions significantly reduce glycated hemoglobin and fasting blood glucose in type 2 diabetes
- Incretin-based therapies outperform placebo for glycemic control and weight loss in type 2 diabetes
- General medical management improves medication adherence and lifestyle outcomes in older adults with type 2 diabetes
- Hyperuricemia affects 22% of type 2 diabetes patients in global meta-analysis
- Retatrutide Demonstrates Dose Dependent Glycemic Control and Weight Loss in Type 2 Diabetes
- Untreated glucose intolerance in pregnancy linked to postpartum metabolic dysfunction similar to treated GDM
- Once-weekly basal insulin improves HbA1c by 0.09% and time in range over daily regimens
- Resveratrol supplementation significantly reduces LDL-C but lacks consistent impact on glycemic indices in type 2 diabetes
- SGLT2 inhibitors associated with lower all-cause mortality in heart transplant recipients with type 2 diabetes
- Single-incision sleeve plus bypass shows short-term safety and metabolic improvement in 3 patients with obesity and T2DM
- Transcriptomic analysis identifies 337 high-confidence genes associated with Type 2 Diabetes in human pancreatic islets
- SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
- Metformin is associated with higher lactate concentrations during exercise in adults with prediabetes and type 2 diabetes
- Semaglutide reduces risk of kidney decline or death in type 2 diabetes and CKD
- Preoperative comorbidities linked to reduced weight loss after metabolic and bariatric surgery in adults
- GLP-1 receptor agonists may reduce cognitive decline in type 2 diabetes patients with dementia
- Evolocumab reduces cardiovascular events in diabetes without known atherosclerosis
- Pancreaticoduodenectomy alters GLP-1 and GIP responses, exploratory meta-analysis finds
- Long-term voglibose use likely caused leukopenia in a 71-year-old man with type 2 diabetes
- scFv-based biologics show potential for immunomodulation in type 1 and type 2 diabetes
- Insulin degludec/liraglutide ranks highest for HbA1c reduction with SUCRA value of 89.4%
- Metabolic subtypes identify Japanese adults with prediabetes at highest or lowest T2D risk
- Eating later in the biological day is associated with impaired glucose regulation and reduced insulin sensitivity
- 37 loci linked to gestational diabetes, 7 novel, in large multi-ancestry meta-analysis
- AI-driven cardiovascular risk prediction in type 2 diabetes shows promise but bias and lack of diversity limit clinical use
- GLP-1 receptor agonists show no increased ocular disorder risk in type 2 diabetes meta-analysis
- GLP-1RAs show lower risk of serious liver events compared with DPP-4 inhibitors in adults with type 2 diabetes
- Real-time CGM improved HbA1c versus SMBG in adults with type 2 diabetes on basal insulin and modern therapies
- Sitagliptin and liraglutide superior for CGM targets in type 2 diabetes
- Thiazolidinediones show lower hepatocellular carcinoma risk than DPP-4 inhibitors, GLP-1RAs, insulin, and sulfonylureas in this network meta-analysis
- SGLT2 inhibitor use associated with increased diabetic ketoacidosis risk, especially with elevated HbA1c
- Paternal metformin use during spermatogenesis shows no increased risk for major congenital malformations in over 11 000 children across five countries
- Resistance training reduces hemoglobin A1c by 0.62% and systolic blood pressure by 3.91 mmHg in type 2 diabetes
- Multicomponent behavioral interventions show sustained HbA1c reduction in type 2 diabetes
- Greater weight loss and supervised exercise reduce diabetes risk in adults with prediabetes
- Lifestyle programs show no significant diabetes incidence reduction in 14 studies of at-risk individuals
- Trans fatty acids from dairy foods show no increased cardiometabolic risk in systematic review and meta-analysis
- SGLT2 and dual SGLT1/2 inhibitors reduce cardiovascular death or heart failure hospitalization risk in type 2 diabetes patients
- Triple oral therapy with metformin, SGLT-2, and DPP-4 inhibitors lowers HbA1c better than dual regimens in adults with type 2 diabetes
- Natural polysaccharides enhance insulin sensitivity and protect pancreatic beta-cells in type 2 diabetes
- Probiotics, synbiotics, and berberine modestly lower fasting glucose and HbA1c in type 2 diabetes
- Women with Type 1 Diabetes have a 2.10 times higher risk of female sexual dysfunction compared to age-matched controls
- Systematic review and meta-analysis of tirzepatide effects on HbA1c and weight in adults with type 2 diabetes
- Network meta-analysis compares exercise types for glycemic control in type 2 diabetes
- Genetic analysis links GLP-1 agonism to pancreatitis risk and sarcopenia in large cohorts
- Meta-analysis identifies rare gene-trait associations across 1.2 million individuals in global biobanks
- Systematic review and meta-analysis of lifestyle interventions for Type 2 Diabetes in West Africa
- Review of lifestyle factors linked to Type 2 Diabetes risk in Qatar
- Meta-analysis finds higher intrapancreatic fat in type 2 diabetes
- CGM may boost treatment satisfaction in type 2 diabetes, but other outcomes unclear
- Narrative review proposes FISI tools for metabolic syndrome and diabetes management across the life cycle
- Case report and review of literature on acute NSTEMI after fluorescein angiography in a 76-year-old woman
- Systematic review of curcumin with piperine for metabolic and cardiometabolic conditions
- Meta-analysis of Mendelian randomization suggests GLP-1 receptor agonism lowers vascular dementia risk
- Meta-analysis: Resistance training improves vascular function in type 2 diabetes
- Review of GLP-1RAs in Type 2 Diabetes and Atherosclerosis Mechanisms
- Meta-analysis of blood pressure levels and outcomes in type 2 diabetes participants
- Systematic review and meta-analysis on VR for Type 2 Diabetes management
- Pediatric Gut Microbiome Links to Metabolic Dysfunction-Associated Steatotic Liver Disease and Type 2 Diabetes
- Network meta-analysis compares bexagliflozin efficacy and safety with other SGLT2 inhibitors in type 2 diabetes
- Systematic review and meta-analysis of HIIT versus MICT for Type 2 Diabetes outcomes
- Meta-analysis of GWAS in Native Hawaiians and Polynesians identifies 25 trait loci for diabetes and obesity traits
- Systematic review of 88 observational studies on missing data reporting in T2DM-MCI research
- Meta-analysis finds Type 2 diabetes linked to poorer survival in solid tumor patients on immune checkpoint inhibitors
- Network meta-analysis compares glucose-lowering therapies for heart failure with reduced ejection fraction and type 2 diabetes
- Systematic Review and Meta-Analysis of Subcutaneous CGM in Elective Surgery
- Systematic review of saponins for type 2 diabetes and its complications
- Digital Health Interventions Show Mixed Results for Cardiovascular Risk Reduction in Type 2 Diabetes Patients Across Weight Categories
- INSTI switching linked to higher metabolic risk in people with HIV
- Tirzepatide improves standard and intensive therapeutic target attainment versus semaglutide in adults with type 2 diabetes
- Personalized diabetes texting with peer support improved glycemic control and remission rates in type 2 diabetes patients
- Afternoon/Evening Exercise May Lower Blood Pressure More Than Morning Exercise: Meta-Analysis
- Systematic review and meta-analysis links Mediterranean diet to improved cardiometabolic markers
- Text messaging plus educational materials improves healthy eating in uncontrolled diabetes
- Systematic review and meta-analysis links Type 2 Diabetes to higher fracture risk across multiple anatomical sites
- Fasting plasma glucose shows higher diagnostic accuracy than HbA1c for undiagnosed diabetes in adults
- Review of NHANES data links metformin use to lower mortality and inflammatory markers in type 2 diabetes
- A 1-month nudge-based dietary intervention increased daily step counts by 1105 steps at 3 months in adults with type 2 diabetes
- Mobile app plus group sessions showed feasibility in Malaysian women with gestational diabetes
- Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
- Essential phospholipids reduced hepatic steatosis and improved HbA1c in patients with MASLD and type 2 diabetes over 6 months
- Reversion of Prediabetes to Normoglycemia Linked to 68% Lower Diabetes Risk
- Ecnoglutide Reduces HbA1c and Body Weight in Type 2 Diabetes: Meta-Analysis
- Meta-analysis finds GLP-1RA plus SGLT2i reduces UACR in type 2 diabetes with kidney disease
- Systematic review and meta-analysis of hypoglycaemia risk prediction models in type 2 diabetes
- GLP-1RAs reduce weight and HbA1c in severe mental illness with low discontinuation rates
- Meta-Analysis Identifies Risk Factors for Adverse Outcomes in MINOCA Patients
- Narrative review discusses pharmacological and lifestyle interventions for type 2 diabetes and psychological health
- Guideline narrative review discusses diabetes risks from immunosuppressive therapy in kidney transplant recipients
- Baseline anti-GIP antibody levels associate with future diabetes-range glycemia in health checkup cohort
- Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
- Review of miRNA associations with high-risk diabetes profiles in midlife women
- Baseline vitamin D levels linked to semaglutide glycemic and weight outcomes in type 2 diabetes
- GenMetS polygenic score association with cardiometabolic risk in Asian populations
- Semaglutide high dose for weight reduction in people with Type 2 Diabetes
- Individual-participant data meta-analysis shows blood-pressure lowering reduces cardiovascular risk in CKD and non-CKD populations
- Machine learning model improves early detection of occult diabetic kidney disease in hospitalized patients
- High LDL-C to HDL-C ratio linked to cardiovascular events in type 2 diabetes with retinopathy
- Observational study suggests multi-omic scores improve Type 2 Diabetes risk assessment in UK Biobank and MESA cohorts
- Meta-analysis suggests Hatha yoga may improve blood pressure and glucose in non-communicable disease patients