N/A
N=58
Attenuation of Pain in Men and Women
Pain
Bottom Line
View on ClinicalTrials.gov: NCT01220414 ↗Enrolled (actual)
58
Serious AEs
0.0%
Results posted
Feb 2018
Primary outcome: Primary: Time for Subject to Reach Pain Threshold — 16.1; 16.0; 15.0; 14.8 seconds
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Naltrexone, then placebo (Drug); Placebo, then Naltrexone (Drug)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Wisconsin, Madison
- Primary completion
- Jan 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Time for Subject to Reach Pain Threshold |
16.1; 16.0; 15.0; 14.8; 28.8; 24.1 | — |
Summary
The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.
Eligibility Criteria
Inclusion Criteria: Healthy men and women
-
Exclusion Criteria
- current cardiac or other chronic diseases (e.g., cancer, diabetes, hypertension, kidney disease); routine use of prescriptive medications; history of vasovagal response to phlebotomy; an allergy to naltrexone; pregnancy; current smokers; current use of recreational drugs; history of substance abuse
Data sourced from ClinicalTrials.gov (NCT01220414). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.