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Phase 2 Completed N=90 Randomized Double-blind Prevention

Comparison of Efficacy of Vitamin D and Vitamin D-calcium Fortified Yogurt Drink in Diabetic Patients

Source: ClinicalTrials.gov NCT01229891 ↗
Enrolled (actual)
90
Serious AEs
0.0%
Results posted
Jan 2012
Primary outcomePrimary: Serum 25-hydroxyvitamin D — 45.6; 76.2; 78.4 nmol/L

Summary

The aim of this study is to evaluate the possible effects of daily intake of yogurt drink fortified with vitamin D alone or with vitamin D + calcium on some selected glycemic, metabolic, inflammatory and oxidative stress markers in patients with type 2 diabetes (T2DM).

Outcome Measures

OutcomeResultp-value
PRIMARY
Serum 25-hydroxyvitamin D
45.6; 76.2; 78.4
SECONDARY
Fasting Serum Glucose (FSG)
203.3; 171.2; 174.3
SECONDARY
Insulin
10.8; 6.5; 6.4
SECONDARY
Hemoglobin A1c (HbA1c)
8.7; 7; 7.8
SECONDARY
Serum Triglyceride (TG)
181.3; 155.2; 161.1
SECONDARY
Serum Total Cholesterol (Tchol)
197.3; 182.8; 178.5
SECONDARY
Serum Low Density Lipoprotein (LDL)
93.5; 91.1; 96.3
SECONDARY
Serum High Density Lipoprotein (HDL)
51.8; 46.1; 48

Eligibility Criteria

Inclusion Criteria:Age:

  • 30 to 50 years,
  • Fasting blood glucose ≥ 126 mg/dl

Exclusion Criteria

  • Receiving vitamin D or calcium or omega-3 supplements within the last three months,
  • On any medication which could potentially influence vitamin D metabolism (notably estrogens, and calcitonin) within the last three months,
  • Any other concomitant disease such as renal, hepatic, and other endocrinological disorders, and malignancies, which could influence vitamin D metabolism.
  • Receiving insulin or any change in the type and/or dose of the current hypoglycemic medications
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01229891). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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