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N/A N=739

Impact of Sperm DNA Integrity on In Vitro Cycles

Male Infertility · Unexplained Infertility · Abortion, Habitual

Enrolled (actual)
739
Serious AEs
Results posted
Mar 2014
Primary outcome: Primary: Pregnancy — 67; 80 participants

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Pediatric, Adult, Older Adult
Sex
Male
Sponsor
Northwell Health
Primary completion
Feb 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Pregnancy
67; 80

Summary

Sperm DNA integrity will be measured via the Toluidine Blue Assay (TBA) for patients undergoing In Vitro Fertilization (IVF); the study will determine correlations, if any, between IVF success and sperm DNA integrity.

Eligibility Criteria

Inclusion Criteria

  • couple undergoing IVF at the Center for Human Reproduction
  • sperm sample given from partner (not a donor)

Exclusion Criteria

  • low sperm concentration (<5 million/cc)
  • using a donor sample
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01232465). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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