N/A
N=100
Efficacy of Nebulized Hypertonic Saline in the Treatment of Acute Bronchiolitis
Bronchiolitis
Bottom Line
View on ClinicalTrials.gov: NCT01238848 ↗Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Aug 2012
Primary outcome: Primary: Hospitalization Days — 5.8; 5.47 days
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Hypertonic saline (Drug); Normal saline (Drug)
- Age
- Pediatric · 0+ yrs
- Sex
- All
- Sponsor
- Hospital General de Niños Pedro de Elizalde
- Primary completion
- Oct 2011
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Hospitalization Days |
5.8; 5.47 | — |
| SECONDARY Length of Oxygen Use |
4; 3.22 | — |
Summary
The purpose of this study is to evaluate the efficacy of hypertonic saline vs. normal saline in the treatment of infants hospitalized for bronchiolitis, regarding length of hospital stay, oxygen requirements and clinical outcome.
Eligibility Criteria
Inclusion criteria
- Infants aged 1 to 24 months, hospitalized for first episode of bronchiolitis, with severity score ≥ 5 points and oxygen saturation ≥ 97%.
Exclusion Criteria
- Chronic respiratory or cardiovascular disease, respiratory failure.
Data sourced from ClinicalTrials.gov (NCT01238848). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.