Phase 2
N=73
Cognitive Stimulation
Substance Use Disorders
Bottom Line
View on ClinicalTrials.gov: NCT01271413 ↗Enrolled (actual)
73
Serious AEs
0.0%
Results posted
Mar 2014
Primary outcome: Primary: Working Memory — 0.86; 0.04 digits recalled
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 2
- Interventions
- Computerized cognitively stimulating activities (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Johns Hopkins University
- Primary completion
- Jul 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Working Memory |
0.86; 0.04 | — |
| SECONDARY Episodic Memory |
— | — |
| SECONDARY Trail-making |
— | — |
| SECONDARY go/No-go |
— | — |
| SECONDARY Addiction Severity Index |
— | — |
| SECONDARY Delay Discounting |
— | — |
| SECONDARY Digit Symbol Substitution Test |
— | — |
Summary
This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking. The study will compare the effects of different versions of the computer tasks. It also will compare the task performance of different groups of people.
Eligibility Criteria
Inclusion Criteria
- age 18-55
- in methadone maintenance or healthy volunteers
- healthy
Exclusion Criteria
- Axis I disorder (except substance abuse and dependence in methadone maintenance patients)
- severe cognitive impairment
- serious untreated medical condition
Data sourced from ClinicalTrials.gov (NCT01271413). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.