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Phase 4 N=100 Randomized Quadruple-blind Treatment

Assessing Maternal Post-partum Pain With Suppositories

Pain

Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Feb 2018
Primary outcome: Primary: Pain Level Twenty Four Hours After Delivery — 1; 2 units on a scale — p=.35

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Belladonna and opioid suppository (Drug); Glycerin Suppository (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
Female
Sponsor
Loyola University
Primary completion
Sep 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Level Twenty Four Hours After Delivery
1; 2 .35
SECONDARY
Number of Patients Taking Additional Pain Medications
40; 47; 8; 5 .30
SECONDARY
Patient Satisfaction
4; 5 .02 sig

Summary

This trial will evaluate whether the routine use of belladonna/opium (B&O) suppositories improve patients' self-reported pain control in the first 24-hours after delivery.

Eligibility Criteria

Inclusion Criteria

  • Anticipated Vaginal or Cesarean delivery at Gottlieb Medical Center or Loyola University Medical Center
  • > 34 weeks gestation at time of delivery
  • > 18 years old
  • No known allergy to belladonna, opium, or vegetable oil suppositories
  • Able to consent and complete study documents

Exclusion Criteria

  • Chronic pain condition or on narcotic medication prior to admission
  • Contraindications to B&O suppositories, including patients with glaucoma, severe hepatic, or renal disease; bronchial asthma; narcotic idiosyncrasies; respiratory depression; convulsive disorders; acute alcoholism; delirium tremens; history of hypersensitivity to any component of product.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01271855). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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