Phase 2
Completed N=83
IV Glucose for Dehydration Treatment
Source: ClinicalTrials.gov NCT01285713 ↗Enrolled (actual)
83
Serious AEs
0.0%
Results posted
Jan 2013
Primary outcomePrimary: Measurement of Serum Ketones Before and After Administration of Intravenous Fluids for Acute Gastroenteritis — 1.10; 2.39 mmol/L — p=0.0003
Summary
To determine whether the addition of dextrose to IV fluids in the treatment of gastroenteritis leads to a decrease in serum ketones. Secondarily, the clinical benefits of dextrose containing fluids in the treatment of gastroenteritis will be assessed.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Measurement of Serum Ketones Before and After Administration of Intravenous Fluids for Acute Gastroenteritis |
1.10; 2.39 | 0.0003 sig |
Eligibility Criteria
Inclusion Criteria
- Males or females age 2 months to 12th birth date
- Gastroenteritis (as diagnosed by ED attending or fellow physician)
- Need for IV fluids
- Dextrose stick of greater than 60 and less than 170
- Parental/guardian English speaking and granting informed consent
Exclusion Criteria
- Underlying chronic disease affecting glucose metabolism or reason/persistence of symptoms: Renal failure, Diabetes Mellitus, Diabetes Insipidus, Metabolic Disorder, VP shunt, Migraine Headaches
- Shock
- Vomiting greater than 72 hours since onset of illness
- Patients that have received IV fluids at an outside institution within 12 hours
Data sourced from ClinicalTrials.gov (NCT01285713). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.