N/A N=23 Randomized Quadruple-blind Basic Science

Intracranial Pressure in Experimental Models of Headache

High Altitude Headache

Bottom Line

View on ClinicalTrials.gov: NCT01288781 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Dec 2011

Primary outcome: Primary: Change in Optic Nerve Sheath Diameter by Ultrasonography — 0.02; 0.02 mm — p=0.98

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Acetazolamide (Drug); Lactose monohydrate (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Bangor University
Primary completion: Aug 2011

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Optic Nerve Sheath Diameter by Ultrasonography	0.02; 0.02	0.98
SECONDARY Change in High Altitude Headache by Visual Analogue Scale	6.4; 7.2	0.63
SECONDARY Change in Blood Oxygen Saturation	10.8; 11.1	0.20
SECONDARY Change in Fluid Balance	342; 147	<0.01 sig
SECONDARY Change in Optic Nerve Sheath Diameter	0.01; 0.00	0.98
SECONDARY Change in Optic Nerve Sheath Diameter	0.01; 0.00	0.98
SECONDARY Change in Optic Nerve Sheath Diameter	0.01; 0.00	0.98

Summary

The purpose of this study is to determine whether increased pressure in the head is elevated in people who suffer from High Altitude Headache. We hypothesise that head pressure will be elevated in people with High Altitude Headache.

Eligibility Criteria

Inclusion Criteria

Member of the Italian High Altitude Research Expeditions

Exclusion Criteria

Are under the age of 18years;
sulfonamide allergy
Liver or kidney disfunction
Have any other uncontrolled medical condition
Or are unable to give consent.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01288781). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.