Phase 4
Completed N=894
Long-Acting Reversible Contraception
Source: ClinicalTrials.gov NCT01299116 ↗Enrolled (actual)
894
Serious AEs
0.1%
Results posted
Jan 2018
Primary outcomePrimary: Contraceptive Method Discontinuation — 300; 62; 142 Participants
◆ Published Evidence
Established
36citations · ~3 / year
Rationale and enrollment results for a partially randomized patient preference trial to compare continuation rates of short-acting and long-acting reversible contraception.
Summary
In the proposed study, women aged 18-29 seeking oral or injectable contraception will be offered an opportunity to try LARC instead; the FDA-approved options include two types of intrauterine products and one type of subdermal contraceptive implant. Over a 24 month period, the experiences of LARC users will be compared to the experiences of those opting for their initial short-acting method.
Linked Publications (3)
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Rationale and enrollment results for a partially randomized patient preference trial to compare continuation rates of short-acting and long-acting reversible contraception.
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Not seeking yet trying long-acting reversible contraception: a 24-month randomized trial on continuation, unintended pregnancy and satisfaction.
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Opportunity, satisfaction, and regret: Trying long-acting reversible contraception in a unique scientific circumstance.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Contraceptive Method Discontinuation |
300; 62; 142 | — |
| SECONDARY Unintended Pregnancy |
47; 6; 13 | — |
| SECONDARY Participant Attitudes to LARC vs SARC |
354; 120; 138; 52; 15; 24 | — |
Eligibility Criteria
Inclusion Criteria
- 18 to 29 years of age;
- sexually active;
- seeking oral or injectable contraception;
- working cell phone;
- working email account;
- willingness to be contacted by the clinic staff or study coordinators; and,
- willingness to complete questionnaires.
Exclusion Criteria
- currently pregnant;
- previous use of a long-acting reversible contraceptive (LARC) method; and,
- medical contraindications for oral contraceptives and injectables.
Data sourced from ClinicalTrials.gov (NCT01299116) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.