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N/A N=281 Randomized Single-blind Diagnostic

Study of Flat Polyp Detection Using New Narrow Band Imaging (NBI) Compared to White Light Colonoscopy - The FIND FLAT Colonoscopy Study

Colorectal Neoplasms · Colonic Polyps · Colorectal Cancer

Enrolled (actual)
281
Serious AEs
0.0%
Results posted
Apr 2017
Primary outcome: Primary: Number of Participants With Nonpolypoid (Flat and Depressed) Colorectal Neoplasm — 33; 43 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Olympus Colonoscope CFHQ190AL (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
VA Palo Alto Health Care System
Primary completion
May 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Nonpolypoid (Flat and Depressed) Colorectal Neoplasm
33; 43
SECONDARY
Percentage of Missed Lesions on Index Colonoscopy.
32.0; 31.4 0.21
SECONDARY
Percentage of Nonpolypoid (Flat) Missed Lesions
7.2; 11.8 0.18

Summary

We hypothesize that high definition narrow band imaging (NBI) colonoscopy compared to high definition white light colonoscopy will detect an increased number of nonpolypoid (flat and depressed) colorectal neoplasm.

Eligibility Criteria

Inclusion Criteria

  • Adult patients referred for routine colonoscopy are eligible

Exclusion Criteria

  • Known Inflammatory bowel disease
  • Referred for endoscopic evaluation and removal of colorectal lesion
  • Personal or family history of polyposis or non-polyposis syndrome
  • Presentation for emergency endoscopy
  • Inability to remove polyp due to coagulopathy or thrombocytopenia
  • Inability to provide informed consent
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01310699). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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