Phase 2 Completed N=243 Randomized Quadruple-blind Treatment

Selegiline Patch for Treatment of Nicotine Dependence

Tobacco Use

Source: ClinicalTrials.gov NCT01330030 ↗

Enrolled (actual)

243

Serious AEs

0.0%

Results posted

Apr 2016

Primary outcomePrimary: Expired-air Carbon Monoxide Confirmed Smoking Abstinence — 24; 25 participants not smoking

Summary

Relapse to smoking is a common problem affecting smokers who seek treatment. The purpose of this study is examine whether selegiline, given in the form of a skin patch, is effective in stopping smoking.

Outcome Measures

Outcome	Result	p-value
PRIMARY Expired-air Carbon Monoxide Confirmed Smoking Abstinence	24; 25	—

Eligibility Criteria

Inclusion Criteria

Smokes greater than 20 cigarettes per day

Exclusion Criteria

History of Parkinson's disease, high blood pressure, or severe liver or kidney disease
Current substance abuse
Mental illness
Skin conditions that could interfere with patch use
Using antidepressant medications (e.g., levodopa/carbidopa, methyldopa, or any MAO inhibitor)
Pregnant or breastfeeding

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01330030). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.