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N/A N=68 Randomized Triple-blind Supportive Care

Effect of an Investigational Multi-Purpose Solution on Lens Moisture

Contact Lens Moisture

Enrolled (actual)
68
Serious AEs
0.0%
Results posted
Apr 2012
Primary outcome: Primary: Mean Ex-Vivo Advancing Contact Angle — 56.7; 59.2 Degrees

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
FID 114675A Multi-Purpose Disinfecting Solution (MPDS) (Device); ReNu Fresh Lens Comfort Multi-Purpose Solution (MPS) (Device); Silicone Hydrogel Contact Lenses (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Alcon Research
Primary completion
Jan 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Ex-Vivo Advancing Contact Angle
59.5; 63.4
PRIMARY
Mean Ex-Vivo Advancing Contact Angle
59.5; 63.4

Summary

The purpose of the study is to evaluate the effect of an investigational multi-purpose disinfecting solution (MPDS) compared to a marketed multi-purpose solution on the moisture of silicone hydrogel contact lenses.

Eligibility Criteria

Inclusion Criteria

  • 18 years of age or older.
  • Wears silicone hydrogel contact lenses on a daily wear basis i.e. disinfects lenses every night).
  • Has successfully worn contact lenses for 5 days, 8 hours per day, prior to baseline visit.
  • Vision is correctable to 20/30 or better in each eye at distance with study lenses at baseline visit.
  • Other protocol-specified inclusion criteria may apply.

Exclusion Criteria

  • Known sensitivity or intolerance to contact lens multi-purpose solutions.
  • Use of any topical ocular OTC or prescribed topical ocular medications.
  • History or current ocular infections or ocular inflammatory events.
  • Ocular surgery within the past year.
  • Medical condition or use of medication that cause ocular side effects.
  • Participation in any investigational study within the past 30 days.
  • Other protocol-defined exclusion criteria may apply.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01341990). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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