N/A N=68 Effect of an Investigational Multi-Purpose Solution on Lens Moisture
Contact Lens Moisture
Primary: Mean Ex-Vivo Advancing Contact Angle — 56.7; 59.2 Degrees
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N/A N=372 Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
Refractive Error · Myopia · Hyperopia
Primary: Likert Scale Questionnaire Item: "I Can Comfortably Wear my Lenses" — 4.2; 4.4 units on a scale
N/A N=121 OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers
Presbyopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score at Day 30 — 13.4; 15.8 units on a scale — p==0.0030
Phase 4 N=73 Direct Application of Systane Complete to Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Difference in Ocular Surface Damage as Measured by the Brien Holden Vision Institute (BHVI Grading Scale) at Two Weeks — 0.44; 1.08; 0.83 Score on a Scale — p=0.30
N/A N=1,171 Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY
Myopia · Hyperopia
Primary: Incidence of Adverse Events — 2; 0; 8; 3 participants
N/A N=29 Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
Myopia · Dry Eye
Primary: Tear Osmolarity — 310; 313; 306 mOsms/L
N/A N=60 Dailies Total 1 Sphere Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Visual Analog Scale (VAS) Contact Lenses Comfort Scores — 44 Score on a scale — p=<0.001
Phase 3 N=246 Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Ametropia
Primary: Best Corrected Visual Acuity — 0.65; 1.33; 98.06; 98.67 Percentage of Participants
N/A N=127 Senofilcon A Investigational Manufacturing Process
Visual Acuity · Comfort · Overall Vision
Primary: Subjective Overall Comfort (Using CLUE ) — 63.3; 65.0 units on a scale
N/A N=70 Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
Myopia · Astigmatism · Refractive Error
Primary: Mean Ex-Vivo Total Lipid Uptake Per Lens — 7.198; 35.879 micrograms
N/A N=26 Dehydration of Omafilcon A Contact Lenses Versus Delefilcon A Contact Lenses
Myopia
Primary: Absolute Change in Water Content (Mean) of Omafilcon A and Delefilcon A — 1.59; 3.82 absolute WC change
N/A N=61 Evaluation of Comfilcon A and Senofilcon A Lenses
Myopia
Primary: Subjective Responses for Comfort Rated on a 0-100 Visual Scale. — 86; 87; 89; 91 units on a scale
N/A N=175 Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers
Refractive Error
Primary: Mean Change From Baseline (Day 0) in Average Corneal Staining Area at Day 30 — -5.04 Percentage of corneal staining
N/A N=104 Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers
Myopia · Astigmatism · Refractive Error
Primary: Change From Baseline (Day 0) in Ocular Comfort Rating at Day 14 — 87.40; 88.79; 81.75; 83.18 Units on a scale
N/A N=56 Refitting Frequent Replacement Lens Wearers Into Clariti 1 Day And 1-Day Acuvue Moist Daily Disposable Spherical Lenses
Myopia
Primary: Lens Handling for Lens Insertion — 9.3; 8.0 units on a scale
N/A N=36 Evaluating the Initial Lens Handling Experience of Neophyte Contact Lens Wearers Fitted With Precision1 and 1-Day Acuvue Moist Contact Lenses
Myopia
Primary: Subjective Ratings of Lens Handling for Insertion Per Intervention — 85; 80; 75; 85 score on a scale — p=0.331
N/A N=15 DAILIES TOTAL1® Lubricity Post Wear
Refractive Error
Primary: Average Coefficient of Friction (CF) at 16 Hours Compared to Unworn — 0.0394; 0.0396 unitless
Phase 3 N=30 Comparison of Lens Care Regimens With a Silicone Hydrogel Lens (Emerald)
Myopia
Primary: High Contrast Visual Acuity — -0.04; -0.04 logMAR
Phase 4 N=46 Evaluation of Systane Complete for the Treatment of Contact Lens Discomfort
Contact Lens Discomfort · Dry Eye
Primary: Contact Lens Symptoms — 20.41; 18.92; 12.86; 17.92 Score on a Scale
N/A N=62 A Prospective Study of Two Daily Disposable Contact Lenses
Myopia
Primary: Mean Change From Baseline in Subjective Contact Lens-related Dryness Symptoms at Week 4 as Assessed by the CLDEQ — -0.21; -0.17; -1.07; -0.92 Units on a scale
N/A N=22 Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
Contact Lens Wear
Primary: Ex Vivo Contact Angle — 104.8; 104.9; 103.3 degrees
N/A N=28 Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses
Myopia
Primary: Absolute Change in Water Content (Mean) of Stenfilcon A and Delefilcon A — 2.82; 2.91 absolute WC change
N/A N=29 DAILIES TOTAL1® - Comparative Assessment of Tear Film Evaporation
Refractive Error
Primary: Tear Film Evaporation Rate — 120.88; 105.63 gm^-2 h
N/A N=72 Ocular Comfort and the "Aging" Lens (ERBIUM)
Refractive Error
Primary: Phase 3: Ocular Comfort, Lens Age 1 Day, Hour 1 — 76; 88 Units on a scale
N/A N=192 Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
Myopia · Hyperopia · Contact Lens Comfort
Primary: Subjective Lens Wear Comfort — 4.3; 4.3 units on a scale
N/A N=36 Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
Refractive Errors
Primary: Average Percent Area of Corneal Staining — 2.93; 0.45; 6.06; 3.52 percentage of area
N/A N=62 Contact Lens Comfort Relative to Meibomian Gland Status
Meibomian Gland Dysfunction
Primary: Comfort as Measured by the Contact Lens Users Experience Questionnaire (CLUE) — 58.67 units on a scale
N/A N=60 A Comparison of Two Daily Disposable Contact Lenses
Myopia
Primary: Visual Acuity — -0.10; -0.10; 0.17; 0.18 logMAR scale
N/A N=42 Comparative Evaluation of Contact Lens Centering of DAILIES® AquaComfort Plus® Versus 1-DAY ACUVUE® MOIST® in Japan
Refractive Error · Myopia · Myopic Astigmatism
Primary: Mean Investigator-Rated Lens Centration — 0.34; 0.73 units on a scale
N/A N=88 Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers
Dry Eye Syndrome · Myopia
Primary: Mean Change From Baseline in Contact Lens-Related Dryness Symptoms at Week 1 and Week 2 — -0.09; -0.29 Units on a scale