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N/A N=130 Randomized Diagnostic

Evaluation of Diagnostic Value of 3-T Magnetic Resonance Imaging (MRI) in Suspected Prostate Cancer

Prostatic Neoplasms

Enrolled (actual)
130
Serious AEs
0.0%
Results posted
Jun 2015
Primary outcome: Primary: Number of Prostate Cancer Diagnoses in MRI and no MRI Groups — 34; 34 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
magnetic resonance imaging, Siemens (Device)
Age
Adult, Older Adult · 40+ yrs
Sex
Male
Sponsor
University of Oulu
Primary completion
Dec 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Prostate Cancer Diagnoses in MRI and no MRI Groups
34; 34
SECONDARY
Number of Positive Biopsies in MRI and no MRI Groups
3.0; 3.0
SECONDARY
Proportion of Clinically Significant Prostate Cancers Detected in MRI and no MRI Groups

Summary

The purpose of the study is to evaluate the usefulness of 3-T magnetic resonance imaging (MRI) in the evaluation of suspected prostate cancer. Men with suspected prostate cancer based on serum prostate-specific antigen antigen (PSA) value are included. Men are randomized to pre-biopsy MRI or no MRI groups in ratio 1:1. Standard transrectal ultrasound guided biopsies will be taken in addition to extra biopsies from lesions suspicious based on MRI evaluation. Hypothesis is that more prostate cancers will be found after MRI evaluation.

Eligibility Criteria

Inclusion Criteria

  • Informed consent
  • Suspected prostate cancer based on PSA value (total PSA 2,5-10 ng/ml and PSA free to total ratio 30
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01357512). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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