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N/A Completed N=93 Randomized Treatment

Evaluation of Learning-Theory-Based Smoking Cessation Strategies

Nicotine Dependence
Source: ClinicalTrials.gov NCT01368653 ↗
Enrolled (actual)
93
Serious AEs
7.5%
Results posted
Nov 2014
Primary outcomePrimary: 4-week Abstinence — 15; 17; 29; 20 participants

Summary

This clinical trial tested whether a new treatment designed to help smokers prepare to quit smoking by practicing quitting several times helped more smokers quit and stay quit than standard treatment with nicotine patch and smoking cessation counseling. The practice quitting treatment tested involved quitting for progressively longer periods of time tailored to individual patterns of smoking. This clinical trial also tested whether non-nicotine cigarettes can help smokers become smoke free after slipping during a stop smoking attempt.

Outcome Measures

OutcomeResultp-value
PRIMARY
4-week Abstinence
15; 17; 29; 20; 3; 9
SECONDARY
10-week Abstinence
5; 11; 2; 1; 36; 26
SECONDARY
Mediators of Treatment Effects: Confidence in Quitting in the Weeks Leading up to the Target Quit Date
4.39; 3.70
SECONDARY
Prolonged Abstinence
14; 20; 1; 6; 27; 17

Eligibility Criteria

Inclusion Criteria

  • 18 years of age or older
  • Smoke cigarettes daily
  • Motivated to quit smoking
  • Able to read and write English
  • Willing and able to complete study visits and cell phone calls

Exclusion Criteria

  • Pregnancy, breastfeeding, planning on becoming pregnant during the study
  • Recent heart attack or heart surgery, heart disease, unstable angina
  • Allergy to adhesives
  • Past negative reactions to nicotine patch
  • Serious skin conditions
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01368653). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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