N/A Completed N=14 Randomized Treatment

Effects of Exercise Training on Fluid Instability in Heart Failure Patients

Source: ClinicalTrials.gov NCT01375673 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2020

Primary outcomePrimary: Bioelectrical Impedance Change — 47.52; 47.1; 41.27; 46.8 Percentage of Extra Cellular Fluid

Summary

Heart Failure (HF) is a significant healthcare concern in the US, with a 120% rise in mortality rates over 15 years costing the country an estimated $37.2 billion in 2009. Veterans are currently impacted at a rate of 5.2%, and cost an average of $14,959/individual/year for those utilizing the VA's Healthcare services. Research has shown that exercise training (ET) improves aerobic capacity, endothelial dysfunction, quality of life, and the ability to tolerate activity within the overall HF population. The purpose of this study is to examine the effects of structured exercise training and specific types of exercise training, walking, bicycling, and resistance training, on the symptom of fluid volume over load or edema in advanced heart failure patients.

Outcome Measures

Outcome	Result	p-value
PRIMARY Bioelectrical Impedance Change	47.52; 47.1; 41.27; 46.8; 42.1; 47.0	—
SECONDARY Body Weight Change	249; 256; 242; 260; 258; 261	—
SECONDARY Health Outcome Measures Change	25.05; 27.25; 18.2; 28.25; 28.55; 29.5	—

Eligibility Criteria

Inclusion Criteria

Advanced Heart Failure
Ability to Walk
Over 21

Exclusion Criteria

Renal Failure
Inability to walk
Physician exclusion

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01375673). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.