N/A N=66 Randomized Treatment

Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma

Ventilator Associated Pneumonia

Bottom Line

View on ClinicalTrials.gov: NCT01382446 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Nov 2013

Primary outcome: Primary: Effectiveness of Chlorhexidine Gluconate Oral Care for Trauma Patients — 30; 29 participants

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Chlorhexidine gluconate (Drug); Toothpaste (Other)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: St. Joseph's Hospital and Medical Center, Phoenix
Primary completion: Apr 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Effectiveness of Chlorhexidine Gluconate Oral Care for Trauma Patients	30; 29	—

Summary

Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.

Eligibility Criteria

Inclusion Criteria

Adults admitted to ICUs located in Tower Two Critical Care Units: Medical, Surgical, Medical #2, and Trauma Intensive Care Units.
Patients will be randomized to either treatment or standard group based on day of admission to Intensive Care Units. No limitation regarding gender, race, and ethnicity so that the sample will reflect "typical" Trauma population.

Exclusion Criteria

All patients admitted under "Doe" Status
All patients with acute cervical spine injuries or facial fractures that oral care will create further harm to the patient (physician order stating "no oral care to be given" will be in chart)
All patients with Oral Trauma or Oral Surgery
All minors (Study will be completed in Adult Critical Care Units)
Patients with allergy to chlorhexidine
Patients without Teeth, or with fewer than 6 teeth

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01382446). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.