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Phase 3 N=331 Randomized Quadruple-blind Treatment

Clinical Study to Assess the Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Middle Ear Infections in Pediatric Patients

Acute Otitis Media

Enrolled (actual)
331
Serious AEs
0.0%
Results posted
Oct 2015
Primary outcome: Primary: Time to Cessation of Otorrhea — 7.69; 22; 3.75 days

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
DF289 (Drug); DF277 (Drug); DF289 plus DF277 (Drug)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
Salvat
Primary completion
Jun 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Time to Cessation of Otorrhea
7.69; 22; 3.75

Summary

The purpose of this study is to determine if the combination of DF289 plus DF277 is safe and effective in treating middle ear infections in children with ear tubes.

Eligibility Criteria

Inclusion Criteria

  • 6 months to 12 years
  • ear tube in the ear which will be treated
  • otorrhea for 3 weeks or less
  • moderate or severe otorrhea

Exclusion Criteria

  • other ear diseases
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01395966). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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