N/A Completed N=21 Randomized Treatment

Modified Adaptive Servoventilation (ASV) Compared to Conventional ASV

Periodic Breathing · Breathing-Related Sleep Disorder

Source: ClinicalTrials.gov NCT01405313 ↗

Enrolled (actual)

Serious AEs

2.4%

Results posted

Mar 2017

Primary outcomePrimary: Apnea/Hypopnea Index (AHI) — 3.9; 6.4 Events per hour — p=0.022

Summary

This study will determine if modified adaptive servoventilation (ASV) is as effective as the conventional ASV in treating periodic breathing. The study will determine if the modified ASV reacts appropriately to reduce apneas and hypopneas and provides suitable levels of positive airway pressure compared to conventional ASV.

Outcome Measures

Outcome	Result	p-value
PRIMARY Apnea/Hypopnea Index (AHI)	3.9; 6.4	0.022 sig
SECONDARY Oxygen Desaturation Index (ODI)	5.2; 8.2	0.016 sig

Eligibility Criteria

Inclusion Criteria

21+ years old
Chronic ResMed ASV therapy patient
Current ASV therapy for at least 4 weeks
Able to understand fully the study information and participation requirements
Provide signed informed consent

Exclusion Criteria

Acute cardiac decompensation
Acute myocardial infarction within last 3 months
Resuscitation within last 3 months
Stroke with swallowing disorders or persistent hemiparesis
Blood pressure test at end expiratory pressure (EEP) 10cmH2O not passed
Untreated restless legs syndrome
Alcohol or drug abuse
Known cancer
Pregnancy
Conditions that could interfere with patients participating in and completing the protocol and/or the investigator deems their enrolment unsuitable

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01405313). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.