N/A N=126 Randomized Single-blind Treatment

Mechanisms of Change, Motivation, and Treatment Outcome in Alcohol Dependence - Posttraumatic Stress Disorder

Alcohol Dependence · Posttraumatic Stress Disorder

Bottom Line

View on ClinicalTrials.gov: NCT01409707 ↗

Enrolled (actual)

126

Serious AEs

0.0%

Results posted

Mar 2014

Primary outcome: Primary: Impact of Event Scale-Revised — 26.00; 19.10; 14.11 units on a scale — p==.068

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Trauma-focused exposure therapy (Behavioral); Motivational enhancement + trauma-focused exposure therapy (Behavioral); Healthy lifestyles sessions (Behavioral)
Age: Adult · 18+ yrs
Sex: All
Sponsor: University of Mississippi Medical Center
Primary completion: Jan 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Impact of Event Scale-Revised	26.00; 19.10; 14.11	=.068
PRIMARY Timeline Follow Back	97.95; 97.83; 92.12	= 0.39

Summary

The purpose of this study is to test if provision of an effective psychotherapy for Post-traumatic Stress Disorder (PTSD), prolonged exposure, can be tolerated in alcohol dependent patients with PTSD and if it is associated with better treatment outcomes compared to an active control condition.

Eligibility Criteria

Inclusion Criteria

Current PTSD
Current Alcohol Dependence
at least one heavy drinking day in the past 60 days

Exclusion Criteria

Psychotic disorder
Untreated bi-polar disorder
benzodiazepine use

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01409707). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.