Transdiagnostic behavior therapy shows comparable efficacy to disorder-specific therapies in veterans with depression, PTSD, and panic disorder
Veterans with depression or anxiety found similar results using transdiagnostic behavior therapy compared to disorder specific treatments
This randomized controlled trial in 304 veterans compared transdiagnostic behavior therapy to disorder-specific therapies for major depressi…
A study of 304 veterans showed that transdiagnostic behavior therapy worked just as well as standard disorder specific treatments. Patients …
IPD meta-analysis identifies risk factors for persistent PTSD and MDD after trauma
Depression Symptoms After Trauma May Predict Long-Term PTSD Risk
This individual participant data meta-analysis synthesized findings from five prospective studies of 2,571 participants in emergency and cri…
New research shows that early depression symptoms after trauma can predict who will struggle with PTSD months later, offering a chance for e…
1-Hz TMS targeting right dlPFC reduced amygdala reactivity and PTSD symptoms in 50 adults with PTSD symptoms compared with sham
Personalized Brain Stimulation Shows Promise For Long Term PTSD Relief
This randomized clinical trial enrolled 50 adults with PTSD symptoms.
Brain scans guide magnetic pulses to reduce fear responses in PTSD patients over several months of recovery time.
PTSD treatment recall study: fewer than one-third accurately described their assigned option
Less than half of patients remember how well their PTSD treatments work
In a study of 887 adults who screened positive for PTSD, participants were given descriptions of seven treatment options and quizzed on reca…
Less than half of patients remember how well their PTSD treatments work, and fewer can correctly identify which therapy focused on trauma.
Early-life adversities predict PTSD in Lebanese healthcare workers after acute stressors
Childhood Trauma Outlasts Recent Shocks
This cohort study of 296 healthcare workers in Lebanon examined the association between acute stressors, early-life adversities, and posttra…
Early childhood pain predicts long-term stress better than recent disasters, meaning past hurt hurts more in the long run than recent bad ev…
Multivariate GWAS identifies 248 loci for internalizing disorder and 591 for major depressive disorder in millions of participants
Millions of people studied to find genetic links to anxiety and depression
This multivariate and multi-ancestry genome-wide association study analyzed millions of ancestrally diverse participants to investigate the …
A massive study of millions of people reveals that anxiety, depression, and PTSD share a common genetic foundation while also having unique …
Systematic review finds TF-CBT most supported for trauma in children under 12
Review compares 12 therapies for trauma symptoms in young children
A systematic review and partial meta-analyses of 127 studies involving 5689 trauma-exposed children ≤12 years found TF-CBT to be the most em…
Trauma-Focused Cognitive Behavioral Therapy is the most supported treatment for young children with trauma, while five other therapies lack …
Surveillance summary describes health care provision for 9/11-related conditions
Health program continues providing care for 9/11 responders and survivors
This surveillance summary describes health care provision for 9/11-related health conditions through the World Trade Center Health Program s…
Since 2011, the World Trade Center Health Program has provided health care for 9/11-related conditions among responders and survivors.
Meta-analysis finds virtual reality exposure therapy reduces anxiety and PTSD symptoms
Can virtual reality help people face their fears? A new analysis suggests it might
A meta-analysis of 26 RCTs involving 1,649 patients with anxiety-related disorders and PTSD found virtual reality exposure therapy significa…
Virtual reality exposure therapy significantly reduces phobia, anxiety, and PTSD symptoms while helping people face their deepest fears.
Systematic review finds elevated heart rate post-trauma associated with PTSD persistence in children
Elevated heart rate after trauma linked to persistent PTSD risk in children
A systematic review and meta-analysis of 21 studies examined prospective biomarkers for PTSD in children and young people exposed to trauma.
A faster heart rate right after trauma may signal that a child is at higher risk for long-lasting PTSD symptoms, according to a new review.
Research across Post-Traumatic Stress Disorder
Related studies from across the Post-Traumatic Stress Disorder family.
Interventions reduce mental health symptoms in people affected by extreme weather events across multiple studies
Helpful actions reduce mental health problems after extreme weather events for many people
A comprehensive review of thirty-three studies reveals that targeted interventions significantly improve mental health outcomes for individu…
A review of thirty-three studies shows that specific actions help people feel better after disasters. These steps lower stress, sadness, and…
Depression screening predicts lower health-related quality of life in ICU survivors
Depression and anxiety symptoms lower health quality for ICU survivors after leaving the hospital
This cross-sectional analysis of pre-randomization data from a randomized controlled trial evaluated 319 intensive care unit survivors. Depr…
A study of 319 ICU survivors found that depression and anxiety symptoms significantly reduce health quality. Screening for these issues is i…
Review of a men's cooking class for male earthquake survivors in Japan
Men’s Cooking Classes Help Earthquake Survivors Reconnect
This narrative review synthesizes qualitative findings from the Red Apron Project's Men's Cooking Class for male survivors of the Great East…
After a devastating earthquake, a simple cooking class helped men reconnect and rebuild their community.
Protocol for COMPASS CBT pilot trial in forcibly displaced Venezuelan adults in Peru
First pilot trial tests new therapy for displaced Venezuelans in Peru
This protocol outlines a randomized pilot trial evaluating COMPASS, an open-source cognitive behavioral therapy program delivered by lay pro…
A new pilot trial will test a low-cost therapy for anxiety, depression, and PTSD in forcibly displaced Venezuelans living in Peru.
Uncensored traumatic video exposure linked to higher PTSD severity in post-October 7 cohort
Watching Trauma Videos May Increase PTSD Risk
This cohort study examined a large group of individuals in the first months following the October 7 events, none directly exposed.
Seeing graphic trauma online can trigger stress even if you were safe.
Narrative review proposes connectomic-guided psychosurgery framework for treatment-refractory patients
Researchers report framework for psychosurgery in treatment-refractory cases
This narrative critical review synthesizes contemporary psychosurgery options for treatment-refractory psychiatric disorders.
A new framework proposes connectomic-guided psychosurgery for treatment-refractory OCD, depression, and related disorders, based on symptom …
Independent skills practice between music therapy sessions linked to fewer symptoms in TBI/PTSD patients
Music Homework Between Sessions Helps Veterans Recover Better
This retrospective observational analysis of military-connected individuals with traumatic brain injury and/or post-traumatic stress disorde…
Simple music exercises at home may help veterans feel better between therapy visits.
Lifetime violence exposure linked to psychiatric outcomes in South African children
Why Domestic Violence May Hurt Children More Than War Zones
This observational cohort study of 974 school-aged children in South Africa found that lifetime violence exposure was associated with increa…
For children in high-violence areas, what happens inside the home matters more for their mental health than what happens on the streets.
Adjunctive vagus nerve stimulation associated with reduced neurobehavioral symptoms in chronic mTBI with PTSD
Vagus nerve stimulation may help chronic brain injury symptoms in PTSD patients
This retrospective post-hoc subgroup analysis of adults with chronic mTBI and PTSD symptoms examined adjunctive non-invasive vagus nerve sti…
A small study suggests non-invasive vagus nerve stimulation could reduce symptoms in people with both chronic brain injury and PTSD.
Mental health syndemics reduce ART adherence and impair viral suppression in people living with HIV
When HIV and Depression Collide, Treatment Suffers
This systematic review and meta-analysis of 32 studies involving people living with HIV (PLWH) examined the impact of mental health-related …
When depression, trauma, and poverty pile onto HIV, people struggle more to take their meds and keep the virus in check.
Autism diagnosis associated with 4-fold higher PTSD risk in Swedish cohort study
Autistic Girls Face a Hidden PTSD Risk. Here’s What Families Should Know
A population-based cohort study of over 450,000 individuals in Sweden found autistic individuals had a 4.37-fold higher risk of developing P…
Autistic girls face a fourfold higher risk of PTSD than boys, with those who also have ADHD at the greatest danger for lasting psychological…
MDMA-assisted therapy shows symptom reduction in PTSD meta-analysis with low certainty evidence
Can MDMA-assisted therapy help people with PTSD? A new analysis suggests it might
A living systematic review and meta-analysis of 6 RCTs with 286 participants found MDMA-assisted therapy reduced PTSD symptoms more than con…
People with PTSD showed greater symptom relief and higher remission rates when treated with MDMA-assisted therapy compared to control condit…
Questions about Posttraumatic Stress Disorder
Can a non-invasive vagus nerve stimulation treatment help adults with chronic mild traumatic brain injury and PTSD?
Early evidence suggests non-invasive vagus nerve stimulation may reduce symptoms in adults with chronic mild TBI and PTSD, but more research is needed.
Full answer →Is there a trial testing hydrocortisone to prevent PTSD after a traumatic event?
Yes, a 2024 Cochrane review found no clear evidence that hydrocortisone prevents PTSD after trauma, though some older studies suggested possible benefit.
Full answer →Are there genetic factors that link PTSD to other internalizing disorders?
Yes, a large genetic study found that PTSD shares many genetic risk factors with other internalizing disorders like anxiety and depression, but also has unique genetic influences.
Full answer →Do early-life adversities increase my risk of developing PTSD after stress?
Yes, early-life adversities increase your risk of developing PTSD after later stress, and this risk persists even after the effects of acute trauma fade.
Full answer →What risk factors make PTSD symptoms last longer after a traumatic event?
Female sex, early-life adversity, acute depression symptoms, and assault-type trauma are linked to longer-lasting PTSD.
Full answer →