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N/A Completed N=542 Randomized Treatment

A Pilot Study of Intra-arrest Therapeutic Hypothermia in Patients Suffering Non-Traumatic Out of Hospital Cardiac Arrest

Source: ClinicalTrials.gov NCT01413399 ↗
Enrolled (actual)
542
Serious AEs
0.0%
Results posted
Dec 2021
Primary outcomePrimary: Number of Participants Who Survived Up To Hospital Discharge — 24; 40 Participants

Summary

The objective of this study will be to assess the frequency of return of spontaneous circulation (ROSC), survival to admission, survival to discharge from the hospital, and neurologic function at time of discharge from the hospital among patients experiencing out of hospital cardiac arrest randomized to receive either intra-arrest induction of therapeutic hypothermia (IATH) or post-arrest therapeutic hypothermia (TH).

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants Who Survived Up To Hospital Discharge
24; 40
SECONDARY
Number of Patients Who Achieve Prehospital Return of Spontaneous Circulation
76; 90

Eligibility Criteria

Inclusion Criteria

  • Cardiac arrest of presumed medical etiology in the out-of-hospital setting

Exclusion Criteria

  • Traumatic Cardiac Arrests
  • Cardiac Arrests Due to hemorrhage
  • Cardiac arrests involving children or young adults
  • Patients presumed to be pregnant
  • Patients with a do not resuscitate
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01413399). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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