Initial intraosseous access shows no survival benefit over intravenous access in out-of-hospital cardiac arrest
New trial shows bone and vein access methods give similar survival rates for heart stop patients
This randomized clinical trial enrolled 1479 adults with non-traumatic out-of-hospital cardiac arrest to compare initial intraosseous vascul…
Doctors compared putting medicine in a bone versus a vein for adults whose hearts stopped outside a hospital. The study found no important d…
Intraosseous route for out-of-hospital cardiac arrest linked to lower outcomes than intravenous access
Using a bone needle instead of a vein line lowers survival chances for cardiac arrest patients
This systematic review and meta-analysis of 245,132 out-of-hospital cardiac arrest patients found that intraosseous access was associated wi…
A huge study of over 245,000 people found that putting medicine into a bone vein works worse than using a standard arm vein. Doctors should …
Immediate coronary angiography showed no 5-year survival benefit versus delayed angiography in OHCA patients without ST elevation
Immediate heart scan after arrest shows no long-term survival gain
This randomized trial enrolled 552 patients resuscitated from out-of-hospital cardiac arrest without ST-segment elevation at nineteen Dutch …
Five years after a sudden cardiac arrest, patients who got an immediate heart scan did no better than those who waited, raising questions ab…
Immediate coronary angiography does not alter 30-day mortality in OHCA survivors without ST elevation
Timing of heart scans does not change survival odds for older cardiac arrest survivors
This randomized controlled trial in 529 patients with out-of-hospital cardiac arrest compared immediate versus delayed coronary angiography.
New research shows rushing heart scans does not save more lives for older people after cardiac arrest without heart attack signs
Meta-analysis of coordinated AED systems for out-of-hospital cardiac arrest in Japan and Poland
Japan's AED System Could Save Lives in Poland
This meta-analysis synthesizes data from Seventeen studies regarding coordinated automated external defibrillator systems for patients with…
A unified national plan for AEDs works far better than scattered devices sitting alone.
Supraglottic airway versus endotracheal intubation shows no overall survival benefit in out-of-hospital cardiac arrest
Study finds airway device choice doesn't change survival after cardiac arrest outside hospitals
A systematic review and meta-analysis of 14,797 patients with out-of-hospital cardiac arrest found no significant difference in return of sp…
Paramedics saving people whose hearts stop outside hospitals find no survival benefit from complex breathing tubes versus simpler airway dev…
Research across Cardiac Arrest
Related studies from across the Cardiac Arrest family.
PEEP Valve in Bag-Valve-Mask CPR for Cardiac Arrest Outcomes
New trial plans to test airway pressure during cardiac arrest
This protocol outlines a trial testing whether a PEEP valve during bag-valve-mask ventilation improves neurological outcomes in out-of-hospi…
A large new trial will test if using a special valve during CPR helps patients with heart attacks have better neurological outcomes.
Manual pressure augmentation did not improve survival to hospital discharge in shockable OHCA
Manual pressure during defibrillation does not improve cardiac arrest survival
This cluster-randomized controlled trial of 560 adults with out-of-hospital cardiac arrest and a shockable rhythm found that manual pressure…
A trial involving 560 patients found that adding manual pressure during shocks did not improve survival rates for those in cardiac arrest.
Standard cardiopulmonary resuscitation improves survival rates in patients with out-of-hospital cardiac arrest
Standard CPR May Improve Survival After Out-of-Hospital Cardiac Arrest
This meta-analysis compared standard cardiopulmonary resuscitation to chest compression-only techniques for patients experiencing out-of-hos…
New data suggests that standard cardiopulmonary resuscitation may improve survival rates for people experiencing a cardiac arrest outside of…
Frailty is associated with higher mortality and poorer neurological outcomes in patients with cardiac arrest
Frailty Linked to Higher Mortality Risk in Cardiac Arrest Patients
This meta-analysis of 12 studies analyzed the impact of frailty on outcomes for adult patients experiencing cardiac arrest. The analysis fou…
Patients with cardiac arrest who are also identified as frail face significantly higher risks of death and poorer neurological outcomes.
Palliative care consultation increases do-not-resuscitate orders and decreases healthcare utilization in cardiac arrest and cardiogenic shock patients
Palliative care linked to better choices for cardiac arrest patients
This narrative review examines palliative care for patients with cardiac arrest and cardiogenic shock and their caregivers. The authors repo…
A review suggests palliative care helps patients with cardiac arrest make decisions about life-sustaining treatments and lowers healthcare c…
Immunomodulatory therapies showed no mortality benefit or neurological harm in 2605 adults after cardiac arrest
New drug review shows no benefit for heart attack survivors
This systematic review and meta-analysis evaluated immunomodulatory therapeutics in adults following in- and out-of-hospital cardiac arrest.…
A large review of immune drugs found no clear benefit for heart attack survivors and did not lower death rates within 30 days.
Mini review examines sudden cardiac death risks in marathon runners across different age groups
Marathon running links to higher heart risk in older men and full-distance participants
This mini review synthesizes evidence on sudden cardiac death (SCD) and coronary artery disease in marathon runners. The authors note that r…
A review of marathon runners shows heart risks vary by age, sex, and race distance, with most events happening near the finish.
Family history, prior arrhythmia, and anterior infarct location independently raise risk of ventricular fibrillation in STEMI patients
Family history and heart attack location raise risk of dangerous heart rhythms in young patients
This meta-analysis of 1807 cases and 2923 controls confirms that family history of sudden death, previous atrial fibrillation, and anterior …
A large study found that family history of sudden death, past atrial fibrillation, and front heart attacks increase the chance of dangerous …
Hands-free carotid ultrasound improves ROSC detection in cardiac arrest
Hands-free ultrasound speeds up heart restart checks for cardiac arrest patients
This randomized controlled trial of 341 adults with in-hospital cardiac arrest found that hands-free carotid ultrasound (CADFlow) led to a…
A new trial shows hands-free ultrasound devices help medical teams detect heart restart success faster and more accurately during cardiac ar…
Narrative review covers cardiovascular conditions and cognitive decline without reported trial data
Your Heart and Brain Are Talking to Each Other
This narrative review addresses a broad scope of cardiovascular conditions, including stroke, heart failure, atrial fibrillation, and ischem…
Imagine your heart and brain as two best friends who never stop texting each other.
FirstCPR cluster randomised trial process evaluation finds leadership and champions drive community BLS uptake
Community groups in Australia showed high engagement with new life support training programs
A multimethod process evaluation of the FirstCPR cluster randomised trial examined delivery, reach, uptake and engagement of multimodal basi…
Social and faith-based groups in Australia successfully adopted new life support training, with 90% engaging in activities while only 18% co…
Plasma proteins linked to HCM severity identified in MYBPC3 carriers and UK Biobank
Could blood proteins predict dangerous heart conditions like sudden cardiac arrest in people with specific gene mutations?
This observational study examined 144 MYBPC3 pathogenic variant carriers and 6,492 UK Biobank participants to identify plasma proteins assoc…
Blood proteins linked to heart failure and sudden cardiac arrest appear in people with specific gene mutations, offering new warning signs f…