Initial intraosseous access shows no survival benefit over intravenous access in out-of-hospital cardiac arrest
New trial shows bone and vein access methods give similar survival rates for heart stop patients
This randomized clinical trial enrolled 1479 adults with non-traumatic out-of-hospital cardiac arrest to compare initial intraosseous vascul…
Doctors compared putting medicine in a bone versus a vein for adults whose hearts stopped outside a hospital. The study found no important d…
Intraosseous route for out-of-hospital cardiac arrest linked to lower outcomes than intravenous access
Using a bone needle instead of a vein line lowers survival chances for cardiac arrest patients
This systematic review and meta-analysis of 245,132 out-of-hospital cardiac arrest patients found that intraosseous access was associated wi…
A huge study of over 245,000 people found that putting medicine into a bone vein works worse than using a standard arm vein. Doctors should …
Immediate coronary angiography showed no 5-year survival benefit versus delayed angiography in OHCA patients without ST elevation
Immediate heart scan after arrest shows no long-term survival gain
This randomized trial enrolled 552 patients resuscitated from out-of-hospital cardiac arrest without ST-segment elevation at nineteen Dutch …
Five years after a sudden cardiac arrest, patients who got an immediate heart scan did no better than those who waited, raising questions ab…
Immediate coronary angiography does not alter 30-day mortality in OHCA survivors without ST elevation
Timing of heart scans does not change survival odds for older cardiac arrest survivors
This randomized controlled trial in 529 patients with out-of-hospital cardiac arrest compared immediate versus delayed coronary angiography.
New research shows rushing heart scans does not save more lives for older people after cardiac arrest without heart attack signs
Meta-analysis of coordinated AED systems for out-of-hospital cardiac arrest in Japan and Poland
Japan's AED System Could Save Lives in Poland
This meta-analysis synthesizes data from Seventeen studies regarding coordinated automated external defibrillator systems for patients with…
A unified national plan for AEDs works far better than scattered devices sitting alone.
Supraglottic airway versus endotracheal intubation shows no overall survival benefit in out-of-hospital cardiac arrest
Study finds airway device choice doesn't change survival after cardiac arrest outside hospitals
A systematic review and meta-analysis of 14,797 patients with out-of-hospital cardiac arrest found no significant difference in return of sp…
Paramedics saving people whose hearts stop outside hospitals find no survival benefit from complex breathing tubes versus simpler airway dev…
Research across Cardiac Arrest
Related studies from across the Cardiac Arrest family.
Serum lactate levels associated with 1.40 odds of unfavorable neurobehavioral outcome in pediatric cardiac arrest
Serum Lactate Levels May Help Predict Outcomes After Cardiac Arrest
This secondary analysis of an RCT involving 213 pediatric patients following out-of-hospital cardiac arrest found that higher serum lactate …
Higher serum lactate levels in children following out-of-hospital cardiac arrest are linked to poorer neurological outcomes and higher morta…
Volume-controlled mechanical ventilation shows no difference in ROSC compared to manual ventilation in cardiac arrest
Trial results show no difference between mechanical and manual ventilation
This meta-analysis of 13 articles, including 6 randomized trials and 7 non-randomized studies, found no significant difference in return of …
New data shows that using a machine to provide volume-controlled ventilation does not improve survival rates for patients in cardiac arrest.
Bystander CPR increases 30-day survival odds by 50% in out-of-hospital cardiac arrest
Bystander CPR Linked to Higher Survival After Cardiac Arrest
This meta-analysis of observational studies involving 2,914,595 events indicates that bystander CPR is associated with significantly higher …
Bystander CPR is linked to significantly higher survival rates for people experiencing cardiac arrest outside of a hospital setting.
Expedited transfer does not reduce mortality in out-of-hospital cardiac arrest
Expedited Transfer Does Not Improve Survival in Cardiac Arrest
This systematic review and meta-analysis of randomized controlled trials in 1,303 adults with out-of-hospital cardiac arrest found that expe…
A review of clinical trials shows that moving patients with cardiac arrest to hospitals faster does not improve survival or neurological rec…
Vasopressin, steroids, and epinephrine triple therapy improves ROSC in in-hospital cardiac arrest
Triple Therapy Shows Promise in Improving Cardiac Arrest Outcomes
This meta-analysis of 3 randomized trials and a network meta-analysis of 21,768 patients evaluates vasopressin, steroids, and epinephrine (V…
A triple therapy of vasopressin, steroids, and epinephrine showed a link to better circulation after cardiac arrest.
High MAP target of 77 mmHg reduces pulmonary vascular resistance in OHCA survivors
Higher Blood Pressure Targets May Improve Heart Function in Cardiac Arrest
This randomized controlled trial sub-study evaluated 730 comatose out-of-hospital cardiac arrest survivors. A higher mean arterial pressure …
A clinical trial suggests that targeting higher blood pressure may improve heart and lung circulation for patients recovering from cardiac a…
Mechanical CPR does not show statistically significant difference from manual CPR for chest injuries
Mechanical CPR does not show higher risk of internal injuries
This meta-analysis evaluates the incidence of cardiothoracic and abdominal injuries during mechanical versus manual cardiopulmonary resuscit…
New data suggests that using a machine for chest compressions during cardiac arrest does not increase the risk of rib fractures or organ dam…
PEEP Valve in Bag-Valve-Mask CPR for Cardiac Arrest Outcomes
New trial plans to test airway pressure during cardiac arrest
This protocol outlines a trial testing whether a PEEP valve during bag-valve-mask ventilation improves neurological outcomes in out-of-hospi…
A large new trial will test if using a special valve during CPR helps patients with heart attacks have better neurological outcomes.
Manual pressure augmentation did not improve survival to hospital discharge in shockable OHCA
Manual pressure during defibrillation does not improve cardiac arrest survival
This cluster-randomized controlled trial of 560 adults with out-of-hospital cardiac arrest and a shockable rhythm found that manual pressure…
A trial involving 560 patients found that adding manual pressure during shocks did not improve survival rates for those in cardiac arrest.
Standard cardiopulmonary resuscitation improves survival rates in patients with out-of-hospital cardiac arrest
Standard CPR May Improve Survival After Out-of-Hospital Cardiac Arrest
This meta-analysis compared standard cardiopulmonary resuscitation to chest compression-only techniques for patients experiencing out-of-hos…
New data suggests that standard cardiopulmonary resuscitation may improve survival rates for people experiencing a cardiac arrest outside of…
Frailty is associated with higher mortality and poorer neurological outcomes in patients with cardiac arrest
Frailty Linked to Higher Mortality Risk in Cardiac Arrest Patients
This meta-analysis of 12 studies analyzed the impact of frailty on outcomes for adult patients experiencing cardiac arrest. The analysis fou…
Patients with cardiac arrest who are also identified as frail face significantly higher risks of death and poorer neurological outcomes.
Palliative care consultation increases do-not-resuscitate orders and decreases healthcare utilization in cardiac arrest and cardiogenic shock patients
Palliative care linked to better choices for cardiac arrest patients
This narrative review examines palliative care for patients with cardiac arrest and cardiogenic shock and their caregivers. The authors repo…
A review suggests palliative care helps patients with cardiac arrest make decisions about life-sustaining treatments and lowers healthcare c…