N/A
N=13,381
Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
Hypertension · Hyperlipidemia · Diabetes · Smoking · Cardiovascular Risk Factor
Bottom Line
View on ClinicalTrials.gov: NCT01420016 ↗Enrolled (actual)
13,381
Serious AEs
3.5%
Results posted
Sep 2018
Primary outcome: Primary: Predicted Annual Rate of Change in 10-year Risk of Fatal or Nonfatal Heart Attack or Stroke — -0.59; 1.66 annualized change in 10 year % cv risk — p=<0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Prioritized Clinical Decision Support (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- HealthPartners Institute
- Primary completion
- Aug 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Predicted Annual Rate of Change in 10-year Risk of Fatal or Nonfatal Heart Attack or Stroke |
-0.59; 1.66 | <0.05 sig |
Summary
The objective of this project is to develop and implement sophisticated point-of-care Electronic Health Record (EHR)-based clinical decision support that (a) identifies and (b) prioritizes all available evidence-based treatment options to reduce a given patient's cardiovascular risk (CVR). After developing the EHR-based decision support intervention, the investigators will test its impact on CVR, the components of CVR, in a group randomized trial that includes 18 primary care clinics, 60 primary care physicians, and 18,000 adults with moderate or high CVR. This approach, if successful, will (a) improve chronic disease outcomes and reduce CVR for about 35% of the U.S. adult population, (b) maximize the clinical return on the massive investments that are increasingly being made in sophisticated outpatient EHR systems, and (c) provide a model for how to use EHR technology support to deliver "personalized medicine" in primary care settings
Eligibility Criteria
Inclusion Criteria
- Practicing general internist or family physician at HealthPartners Medical Group (HPMG)
- Provide ongoing care for 200 or more adult patients with 10 year CVR >=10%
Exclusion Criteria
- PCP not practicing in HPMG clinic
- Patient age greater than 80 years
- Patient Charlson comorbidity score greater than 3
Data sourced from ClinicalTrials.gov (NCT01420016). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.