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Phase 2 N=245 Randomized Double-blind Prevention

Prevention of Post Sexual Assault Stress

Drug Use · Drug Abuse · Posttraumatic Stress Disorder

Enrolled (actual)
245
Serious AEs
0.8%
Results posted
Apr 2016
Primary outcome: Primary: Drug Abuse Screening Test (DAST-10) — 1.97; 2.03; 1.18 units on a scale — p=.24

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
PPRS (Behavioral); PIRI (Behavioral)
Age
Pediatric, Adult, Older Adult · 15+ yrs
Sex
Female
Sponsor
Medical University of South Carolina
Primary completion
Dec 2013

Outcome Measures

OutcomeResultp-value
PRIMARY
Drug Abuse Screening Test (DAST-10)
1.97; 2.03; 1.18 .24
PRIMARY
Alcohol Use Disorders Identification Test (AUDIT)
7.21; 7.53; 8.15 .89
PRIMARY
Cigarettes (Estimated Number)
49.94; 87.29; 118.04; 54.63; 67.73; 84.47 .01 sig
PRIMARY
Amount of Alcohol Use
15.33; 13.92; 19.90; 8.29; 14.32; 11.49 .63
PRIMARY
Marijuana Use Frequency
1.98; 2.48; 2.12; 2.75; 1.39; 2.12 .83
SECONDARY
Any Other Illicit Drug Use
6; 0; 2; 4; 3; 2 .37
SECONDARY
Non-medical Use of Prescription Drugs Frequency
1.56; .08; .54; .81; .75; .16 .012 sig
SECONDARY
PTSD Symptom Scale Self-Report (PSS-SR)
26.98; 29.07; 24.49; 23.98; 23.33; 21.70 .15

Summary

The purpose of this study is to evaluate whether a brief intervention in video format, that includes education about reactions to assault and modeling of adaptive coping strategies, designed to reduce post assault drug use or abuse and PTSD and shown to recent victims of sexual assault at the time of receipt of post assault medical care is associated with better post-assault outcomes as compared to a comparable length video that includes pleasant imagery and relaxation instruction or standard care.

Eligibility Criteria

Inclusion Criteria

  • Seeking medical care after recent sexual assault

Exclusion Criteria

  • Active psychosis Active suicidality Cognitive impairment Non-English speaking Severe injury
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01430624). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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