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N/A N=40 Randomized Single-blind Prevention

Desflurane Versus Propofol in the Sitting Position

Cerebral Ischemia

Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Aug 2013
Primary outcome: Primary: Regional Cerebral Oxygen Satuation (rSO2) — 77.4; 72.5; 76; 70 percentage of rSO2 (%)

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
propofol (Drug); Desflurane (Drug); alfentanil (Drug); Rocuronium (Drug)
Age
Adult, Older Adult · 20+ yrs
Sex
All
Sponsor
Gachon University Gil Medical Center
Primary completion
Aug 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Regional Cerebral Oxygen Satuation (rSO2)
77.4; 72.5; 76; 70; 75.2; 70

Summary

The investigators hypothesized that both propofol and desflurane would decrease the regional oxygen saturation (rSO2) but propofol is likely to reduce rSO2 more than sevoflurane when patients are raised to the sitting position.

Eligibility Criteria

Inclusion Criteria

  • Forty patients,
  • ASA class I or II,
  • undergoing shoulder arthroscopy

Exclusion Criteria

  • Patients with history of cerebrovascular disease, coronary occlusive disease and/or obesity (body mass index > 30) were excluded from this study.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01436799). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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