Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
Traditional Chinese medicine metabolites protect brain cells from damage
This review examines the utility of Traditional Chinese medicine (TCM) metabolites for neurological conditions including Alzheimer's disease…
A review shows Traditional Chinese medicine metabolites protect brain cells through anti-inflammatory and anti-oxidative stress actions, off…
Individual patient data meta-analysis links blood neurofilament light chain levels to ischemic stroke outcomes
High blood NfL levels predict worse outcomes after ischemic stroke
This individual patient data meta-analysis evaluated blood neurofilament light chain (NfL) levels in 2872 adult patients within 30 days afte…
A meta-analysis of 2,872 patients found that higher blood neurofilament light chain levels within days of an ischemic stroke predict greater…
Glomerular Hyperfiltration Linked to Higher Mortality in Stroke and TIA Patients
Stroke Survivors Overlooked Danger Doubles Death Risk
An individual patient data meta-analysis of 11,175 patients with stroke or TIA found that glomerular hyperfiltration (eGFR > age- and sex-ad…
• Kidney overwork sharply raises death risk after stroke • Helps stroke patients and their doctors monitor better • Not yet routine care nee…
Health and Wellness coaching for blood pressure control in minor stroke or TIA
Your Daily Habits Could Shield You From Another Stroke
This is a Phase III randomized controlled trial protocol for adults with minor stroke or transient ischaemic attack in New Zealand. The stud…
• Lifestyle coaching cuts blood pressure better than standard care.
Sex differences in outcomes after stroke in NVAF with ASCVD: a post hoc analysis
Women and Men With AFib and Clogged Arteries Share Same Stroke Risk
This post hoc analysis of an RCT included 222 patients with recent ischemic stroke or TIA, NVAF, and ASCVD. No significant sex differences w…
Women and men with AFib and clogged arteries face similar risks for stroke, heart attack, and bleeding over two years.
Exercise reduces blood pressure after stroke or TIA: systematic review and meta-analysis
Exercise lowers blood pressure after stroke, review finds
This systematic review and meta-analysis of 25 studies found that aerobic exercise reduces systolic blood pressure by 3.79 mmHg and diastoli…
A review of 25 studies finds aerobic and combined exercise can significantly lower blood pressure in stroke survivors.
Narrative review examines resveratrol in Alzheimer's, Parkinson's, MS, and cerebral ischemia with noted limitations
This Common Food Compound May Shield Your Brain From Damage
This narrative review evaluates resveratrol across Alzheimer's disease, Parkinson's disease, multiple sclerosis, and cerebral ischemia.
A natural compound found in berries shows promise for protecting brain cells, but human proof is still missing.
Asundexian added to antiplatelet therapy reduces recurrent stroke risk without increasing major bleeding in high-risk patients
New drug lowers stroke risk in high-risk patients without increasing bleeding
This phase 3 trial evaluated asundexian added to standard antiplatelet therapy in patients with noncardioembolic ischemic stroke or high-ris…
A new daily pill lowers stroke risk in high-risk patients without increasing bleeding, offering a safer option for preventing clots after a …
Systematic review finds low-certainty evidence against endovascular therapy superiority in vertebral artery stenosis
Stents May Not Stop Strokes in Narrowed Neck Arteries
This systematic review evaluated endovascular therapy versus medical treatment alone in adults with symptomatic vertebral artery stenosis.
Stents might not stop strokes in narrowed neck arteries better than medicine alone for people with blocked blood flow to the back of the bra…
In ostial vertebral artery stenosis, DES implantation showed 12.56% ISR incidence with TEG parameters as independent predictors
Why a Common Neck-Artery Stent Sometimes Quietly Re-Narrows in the First Year
This single-center retrospective cohort study evaluated 446 patients undergoing drug-eluting stent (DES) implantation for ostial vertebral a…
About 1 in 8 patients with neck-artery stents developed re-narrowing within a year, but a specialized blood-clotting test may help doctors s…
Lp-PLA2 activity does not significantly modify dual antiplatelet therapy efficacy in minor stroke/TIA with CYP2C19 loss-of-function alleles
Blood enzyme levels don't change which stroke prevention drug works better, study finds
This subgroup analysis of the CHANCE-2 RCT examined 5919 patients with minor stroke/TIA and CYP2C19 loss-of-function alleles.
A simple blood test for inflammation doesn't predict which stroke prevention drug works best for patients with a specific genetic trait.
Research across Stroke
Related studies from across the Stroke family.
Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
Atractylenolide III shows promise for brain and nerve injuries in lab models
This narrative review summarizes preclinical evidence that Atractylenolide III exerts neuroprotective effects in models of cognitive impairm…
Atractylenolide III looks like a helpful option for brain and nerve damage in early lab tests, though human trials are needed.
Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
Treatment stabilized some symptoms but not others in a single patient case
This case report describes a 72-year-old female with ANCA-associated vasculitis, Evans syndrome, and cerebral infarction treated with cortic…
A 72-year-old woman with complex blood vessel disease saw some health markers improve while others remained poor after specific treatments.
Evidence summary on glycemic variability management in ICU patients with cerebral infarction
ICU Guidelines Suggest Managing Blood Sugar Swings During Feeding
This evidence summary synthesizes 18 documents on glycemic variability management during enteral nutrition for adult ICU patients with cereb…
Guidelines advise managing blood sugar swings in ICU patients receiving tube feeding, noting that individual adjustments depend on local res…
Meta-analysis of preclinical studies suggests ligustrazine improves outcomes in cerebral ischemia-reperfusion injury
New data shows Ligustrazine helps brain recovery after stroke-like events in animals
This meta-analysis of preclinical animal studies evaluated ligustrazine for cerebral ischemia-reperfusion injury. Pooled results from 381 an…
New research suggests a specific plant compound could help the brain recover after blood flow is restored following a blockage
Review of SPMs for stroke notes promising neuroprotective effects with delivery limitations
Your Brain's Natural Healing Helpers Could Change Stroke Recovery
This review examines the role of exogenous administration of SPMs or their stable analogs in cerebral ischemia-reperfusion and stroke. The a…
After stroke, the brain's own healing chemicals might prevent lasting damage, but human trials haven't started yet.
Non-immersive virtual reality for upper limb motor function after chronic stroke
New Virtual Reality Training Helps Stroke Patients Regain Arm Movement
This randomized controlled trial in 26 patients with chronic middle cerebral artery stroke compared non-immersive virtual reality to convent…
A new virtual reality tool helps stroke patients regain arm movement skills in a way that standard therapy alone cannot match.
Narrative review discusses ischemia-reperfusion injury mechanisms and future therapeutic strategies
Heart and Brain Damage After Blood Flow Loss May Be Linked by Shared Cell Death Pathways
This narrative review addresses myocardial and cerebral ischemia-reperfusion injury.
This research reveals how heart and brain cells may die together through linked pathways, opening new doors for treatments that protect both…
Retrospective study of endovascular treatment for sICAS shows no significant difference in 30-day stroke or death between early and delayed groups
Timing of treatment did not change stroke risk for patients with brain vessel blockages
This retrospective single-center study analyzed 174 consecutive patients with symptomatic intracranial atherosclerotic stenosis undergoing i…
For people with blocked brain vessels, getting endovascular treatment early versus later did not significantly lower the risk of stroke or d…
First-line suction aspiration versus combination technique for acute cerebral infarction in a multicenter trial
Imagine waking up unable to move one side of your body. This sudden loss of control is a stroke. Every minute counts when a blood vessel in the brain is blocked. Doctors race to open the vessel and save brain tissue. Time is the most important factor in recovery
This prospective, randomized, multicenter, noninferiority, open-label trial enrolled 1136 patients with acute cerebral infarction amenable t…
Strokes are a leading cause of disability worldwide.
Higher CRP and D-dimer levels associated with cerebral infarction in children with Mycoplasma pneumoniae pneumonia
High Fever Warning: Two Blood Tests Spot Stroke Risk in Kids
This retrospective cohort study included 2,947 children diagnosed with Mycoplasma pneumoniae pneumonia.
Two simple blood tests can spot stroke risk in kids with pneumonia before brain damage happens, helping doctors catch rare cases early.
Cerebral infarction common in tuberculous meningitis and linked to disease severity and arterial occlusion
Could blood thinners or specific treatments make brain strokes worse in severe meningitis?
This secondary analysis of the ACT-TBM randomized trial examined 226 patients with tuberculous meningitis at two tertiary centers in India.
Patients with tuberculous meningitis and blocked arteries were much more likely to develop strokes, especially if they received modified tub…
Review synthesizes electroacupuncture effects on cerebral ischemia-reperfusion injury mechanisms
Could electroacupuncture protect the brain from injury, and what does the current review tell us?
This narrative review examines the role of electroacupuncture in addressing cerebral ischemia-reperfusion injury.
Electroacupuncture may shield the brain from stroke-related damage by reducing inflammation and protecting cells, though real-world safety a…