N/A
N=120
Cognitive-Behavioral Therapy and Supportive Psychotherapy for Body Dysmorphic Disorder
Body Dysmorphic Disorder · Obsessive-Compulsive Spectrum Disorder · Anxiety Disorders · Somatoform Disorders
Bottom Line
View on ClinicalTrials.gov: NCT01453439 ↗Enrolled (actual)
120
Serious AEs
6.7%
Results posted
Jul 2020
Primary outcome: Primary: Body Dysmorphic Disorder Symptoms (as Measured by the BDD-YBOCS) — 32.21; 31.49; 26.92; 27.27 score on a scale — p=<.01
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Cognitive Behavioral Therapy (Behavioral); Supportive Psychotherapy (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Massachusetts General Hospital
- Primary completion
- Jan 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Body Dysmorphic Disorder Symptoms (as Measured by the BDD-YBOCS) |
32.21; 31.49; 26.92; 27.27; 24.34; 25.09 | <.01 sig |
| SECONDARY Insight Regarding BDD Beliefs (as Measured by the BABS) |
17.2459016; 15.4067797; 14.7500000; 13.3090909; 14.5128205; 12.8500000 | .10 |
| SECONDARY Depressive Symptoms (as Measured by the BDI-II) |
22.1639344; 22.8620690; 18.6923077; 21.4035088; 16.9591837; 19.3076923 | .05 |
| SECONDARY Life Satisfaction (Q-LESQ-SF) |
48.7500000; 50.6961259; 49.6648352; 51.7857143; 61.0119048; 57.6190476 | .04 sig |
| SECONDARY Treatment Credibility (Credibility/Expectancy Rating Scale) |
7.10; 6.64; 7.19; 6.28 | 0.0095 sig |
| SECONDARY Beliefs About Appearance (as Measured by the ASI-R) |
— | — |
| SECONDARY Neuropsychological Functioning (as Measured by the ROCF) |
— | — |
| SECONDARY Information Processing (as Measured by the ERT) |
— | — |
| SECONDARY Sheehan Disability Scale (SDS) |
16.3333333; 17.4406780; 15.1000000; 15.5000000; 11.7142857; 12.2222222 | .30 |
| SECONDARY Treatment Satisfaction (CSQ-8) |
28.02; 26.60; 29.40; 27.56 | 0.0235 sig |
| SECONDARY Treatment Expectancy (Credibility/Expectancy Rating Scale) |
58.36; 50.19; 56.00; 46.73 | 0.0069 sig |
Summary
The purpose of this study is to learn more about two different types of psychotherapy to help individuals who have body dysmorphic disorder (BDD). BDD is a severe, often chronic, and common disorder consisting of distressing or impairing preoccupation with perceived defects in one's physical appearance. Individuals with BDD have very poor psychosocial functioning and high rates of hospitalization and suicidality. Because BDD differs in important ways from other disorders, psychotherapies for other disorders are not adequate for BDD. Despite BDD's severity, there is no adequately tested psychosocial treatment (psychotherapy) of any type for this disorder. This study will compare the effectiveness of Cognitive Behavioral Therapy and Supportive Psychotherapy as well as predictors of improvement.
Eligibility Criteria
Inclusion Criteria
- Outpatient men and women age 18 and older
- DSM-IV BDD or its delusional variant for at least 6 months
- BDD is the most problematic psychiatric disorder (in the patient's and clinician's opinion) and the primary reason for seeking treatment
- Score of 24 or higher on the BDD-Yale-Brown Obsessive Compulsive Scale
Exclusion Criteria
- Current clinically significant suicidality and/or score on the BDI-II suicide item (#9) > 1
- Any clinical features requiring a higher level of care
- Mental retardation or borderline intellectual functioning (estimated IQ 10 sessions of CBT for BDD
- Subjects cannot be receiving any other psychotherapy or begin such treatment during the study
- Patients can be receiving psychotropic medication if they have taken a stable dose for at least two months before the study baseline assessment and the dose remains stable during the study.
- Presence of any behavior (e.g., violence) that would interfere with full cooperation with the protocol.
Data sourced from ClinicalTrials.gov (NCT01453439). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.