N/A
N=20
Combined Electroencephalogram, Magnetic Resonance Imaging-Positron Emission Tomography of Dexmedetomidine Induced Sleep
Dexmedetomidine Induced Sedation
Bottom Line
View on ClinicalTrials.gov: NCT01485380 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Oct 2014
Primary outcome: Primary: Number of Participants With Changes in the Brains Default Mode Network. — 16 participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- dexmedetomidine (Drug)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Massachusetts General Hospital
- Primary completion
- Jul 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Changes in the Brains Default Mode Network. |
16 | — |
Summary
The investigators are doing this research study to find out how and where dexmedetomidine, a sedative anesthetic, acts in the brain. The investigators will do this by using a machine that records the brains electrical activity, called an electroencephalogram (EEG), and brain imaging scans to look at the brain.
Eligibility Criteria
Inclusion Criteria
- American Society of Anesthesiologists (ASA) physical status I
- 18 to 35 years of age
Exclusion Criteria
- MRI and/or PET screening criteria not met
- Abnormal sleep habits/known or suspected sleep disorder(s)
- Taking medication that alters sleep, cognitive function, or both -History of a known neurological or psychiatric problem -Younger than 18 or older than 35 years of age
Data sourced from ClinicalTrials.gov (NCT01485380). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.