N/A
Completed N=35
Efficacy Study of Korean Red Ginseng to Treat Depression
Source: ClinicalTrials.gov NCT01496248 ↗Enrolled (actual)
35
Serious AEs
0.0%
Results posted
Oct 2014
Primary outcomePrimary: Depression Residual Symptom Scale — 21.8 units on a scale — p=<0.05
Summary
The purpose of this study is to determine whether Korean Red Ginseng are effective in the treatment of the residual symptoms of depression as an adjuvant treatment.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Depression Residual Symptom Scale |
17.5 | <0.05 sig |
| SECONDARY Visual Analogue Scale |
28.0 | <0.05 sig |
| SECONDARY Montgomery Asberg Depression Rating Scale |
4.4 | <0.05 sig |
| SECONDARY Clinical Global Index |
2.4 | <0.05 sig |
Eligibility Criteria
Inclusion Criteria
- Outpatients who met Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for major depressive disorder.
- Those who are in remission, which is defined as a MADRS score 8 on two consecutive visits at a 4-week interval.
- Their primary psychiatric clinician determined that they would benefit from an adjuvant treatment of Korean red ginseng for residual symptoms.
Exclusion Criteria
- Those who have a history of substance abuse or dependence within 1 month.
- Those who have clinically significant abnormal laboratory values or any other abnormal baseline laboratory findings considered by psychiatrists to be indicative of conditions that might affect the study results.
- Those who have a past history of hypersensitivity or intolerance to Korean red ginseng.
- Those who participated in clinical trials within 1 month before entering the study entry.
- Those who are pregnant or are breast feeding.
- Those who have a immediate risk of harming self or others or history of suicide attempts in the year before the screening precluded inclusion in the study.
- The patients unable/unlikely to comprehend/follow the protocol.
Data sourced from ClinicalTrials.gov (NCT01496248). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.