N/A
N=60
Saphenous Nerve Block vs. Femoral Nerve Block for Total Knee Arthroplasty
Difference Between Femoral Nerve Block and Saphenous Block
Bottom Line
View on ClinicalTrials.gov: NCT01505374 ↗Enrolled (actual)
60
Serious AEs
0.0%
Results posted
May 2017
Primary outcome: Primary: Visual Analogue Scale Pain Score — 2.81; 2.47 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Study Technique (Procedure); Control Technique (Procedure)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- Hospital for Special Surgery, New York
- Primary completion
- Sep 2013
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analogue Scale Pain Score |
2.81; 2.47 | — |
| SECONDARY Tracking Total Opioid Usage |
133.11 | — |
| SECONDARY Preoperative and Postoperative Thigh Muscle Strength in Both Legs |
17.06; 17.24; 2.86; 2.45; 5.00; 5.08 | — |
| SECONDARY Patient Satisfaction With Nerve Blocks |
8; 8.4 | — |
| SECONDARY Duration of Motor and Sensory Blockade |
— | — |
| SECONDARY Rating the Success of the Nerve Blocks |
— | — |
| SECONDARY Postoperative Complications |
— | — |
Summary
Currently, the regional anesthetic standard of care for total knee replacement surgery is combined spinal/epidural to provide long-lasting pain relief with or without a femoral nerve block (FNB). The femoral nerve block refers to a technique that your anesthesiologist can use to numb the thigh muscle for approximately 18 hours after surgery. While this technique offers significant pain relief, it is possible it may cause muscle weakness and increase patients' recovery times. Hence there is a need for an alterative anesthetic technique, one that may help minimize postoperative pain as effectively as a femoral nerve block, while not causing weakness of the thigh muscle.
The saphenous nerve, a branch of the femoral nerve, provides sensation to the knee. Thus it is hypothesized by "blocking" or anesthetizing the saphenous nerve with local anesthetic closer to where it branches off, the area around and below the knee will feel numb. Yet unlike the femoral nerve block, the thigh muscle itself will still be able to function.
For patients undergoing two total knee replacements at one time or bilateral total knee replacement, they will be randomly assigned to receive a femoral nerve block on one leg and a saphenous block on the other. Pain levels will be measured and thigh muscle strength will be tested using a dynamometer before surgery, 6-8 hours following anesthesia administration, and on postoperative days 1 and 2.
Eligibility Criteria
Inclusion Criteria
- All patients ages 40-80 undergoing Bilateral Total Knee Replacement
- Planned use of neuraxial anesthesia
- Ability to follow study protocol
Exclusion Criteria
- Contraindication to a spinal or epidural anesthestic
- Not a candidate for bilateral total knee replacement
- Chronic opioid use (defined as daily or almost daily use of opioids for >3 months)
- Hypersensitivity and/or allergy to local anesthetics
- Intraoperative use of any volatile anesthetic
- Patients with pre-existing neuropathy on the operative limb
- Contraindication to femoral nerve block or saphenous nerve block
- Allergy to any of the study medications
- American Society of Anesthesiologists (ASA) Class 4-5
- Non-English speaking patients
Data sourced from ClinicalTrials.gov (NCT01505374). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.