N/A N=60 Saphenous Nerve Block vs. Femoral Nerve Block for Total Knee Arthroplasty
Difference Between Femoral Nerve Block and Saphenous Block
Primary: Visual Analogue Scale Pain Score — 2.81; 2.47 units on a scale
Clinical Trial Search
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N/A N=94 Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Total Knee Arthroplasty
Primary: Quadriceps Muscle Strength — 7.3; 2.2 kilogram-force
N/A N=80 Saphenous Nerve Block for Foot and Ankle Surgery
Saphenous Nerve Block
Primary: Block Success — 18; 22 participants — p=0.25
N/A N=32 Evaluation of Continuous Saphenous Nerve Block to Supplement a Continuous Sciatic Nerve Block After Ankle Surgery
Orthopedic Surgery of Lower Extremity
Primary: Verbal Pain Scores — 4.2; 5.4 units on a scale
Phase 4 N=132 Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength
Anterior Cruciate Ligament Tear · Knee Meniscus Tear
Primary: Change in Quadriceps Strength Related to the Nerve Block — -0.42; -0.55; -3.19; -0.77 Newtons
Phase 3 N=94 Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Arthropathy of Knee
Primary: Mean Distance Ambulated at 24 Hours Post Operatively — 70.2; 48.44 feet
N/A N=40 Femoral/Sciatic Block for Knee Surgery
Knee Injuries
Primary: Analgesic Efficacy — 0; 0.1; 0.6; 3.0 units on a scale — p=<0.05
Phase 4 N=86 Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction
Anterior Cruciate Ligament Injury
Primary: Quadriceps Muscle Activation as Assessed by Surface Electromyography (sEMG) — 266.5; 212.5 microvolts (uV)
N/A N=80 Femoral Triangle and Adductor Canal Blocks Versus Femoral Nerve Block for Total Knee Arthroplasty
Total Knee Arthroplasty
Primary: Extent of Motor Blockade — 18; 29; 13; 5 Participants — p=<0.01
N/A N=80 Posterior Capsular Injection With Femoral Nerve Block for Total Knee Arthroplasty
Posterior Knee Infiltration
Primary: Pain Intensity — 3.5; 3.2; 2.1; 1.5 pain score
N/A N=16 Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty
Osteo Arthritis Knee
Primary: Pain Intensity as Measured by 11-point Verbal Numeric Rating Scale (NRS-11) for Pain. — 7.0; 6.0; 4.0; 6.0 units on a scale
Phase 4 N=68 Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control
Internal Derangement of Knee
Primary: Post op Pain Score — 5.5; 3.9 units on a scale
N/A N=50 Lumbar Plexus Block vs Fascia Iliaca Block After Hip Arthroscopy
Hip Arthroscopy · Nerve Block
Primary: Pain Score Change — 3; 1.72 change in score on a scale
Phase 4 N=80 Fast Track Total Knee Arthroplasty: Local Infiltration Analgesia vs Femoral Nerve Block
Arthroplasty, Replacement, Knee
Primary: Stair Climbing Task (SCT) — 14.3; 13.8 seconds
Phase 4 N=104 Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients
Hip Fractures · Analgesia · Femoral Nerve
Primary: Pain Score Change — 4; 2 units on a scale
Phase 4 N=80 Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty
Postoperative Pain Following Knee Arthroplasty
Primary: Hours Until Discharge Readiness — 61; 55 hours
N/A N=50 Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
Postoperative Pain
Primary: Visual Analogue Scores (VAS) - Pain Scores Measured in mm (0-100) — 59.4; 30.2 units on a scale — p=0.001
N/A N=70 Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Regional Anesthesia · Sciatic Nerve Block
Primary: Average Pain — 2.7; 3.4 score on a scale
Phase 4 N=24 Continuous Adductor Canal Nerve Blocks: Relative Effects of a Basal Infusion v. Hourly Bolus Doses
Healthy Human Volunteers
Primary: Tolerance to Cutaneous Electrical Current — 26.6; 27.1 mA
Phase 3 N=42 Comparing Ways to Freeze the Nerve That Provides Thigh Sensation
Meralgia Paresthetica
Primary: Anesthesia Related Time — 554; 480 seconds — p=0.05
Phase 4 N=165 Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
Total Knee Arthroplasty
Primary: Maximum Pain Post-Operative Day (POD) 1 (Morning) — 3; 4; 4.5 units on a scale — p=0.144
Phase 3 N=15 Comparative Evaluation of Lumbar Plexus and Suprainguinal Fascia Iliaca Compartment Blocks
Orthopedic Disorder
Primary: Total Time to Perform the Regional Anesthesia Technique — 3; 6 minutes
Phase 4 N=30 Peripheral Nerve Blocks for Above-the-knee Amputations
Peripheral Vascular Diseases · Hyperglycaemia (Diabetic) · Hypertension
Primary: Peripheral Nerve Block Success as a Primary Anesthetic — 1 Participants
Phase 4 N=100 Serratus Plane Versus Paravertebral Nerve Blocks for Breast Surgery
Breast Surgery
Primary: Mean/Median Numeric Rating Scale Pain Score Within the Recovery Room — 4; 0 score on a scale — p=0.001
Phase 4 N=62 Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty
Pain, Postoperative · Total Knee Arthroplasty (TKA)
Primary: Time to Achieve Physical Therapy Discharge Criteria as Measured by 75-feet Walk Test. {Number of Hours After Conclusion of Surgery} — 67.3; 66; 46.5 Hours — p=0.355
N/A N=50 Efficacy of Fascia Iliaca Block Versus Intraoperative Nerve Infiltration During Anterior Hip Replacement Surgery
Pain, Postoperative
Primary: Postoperative Pain During PACU Admission — 40; 36 units on a scale
Phase 4 N=84 Hip Scope Fascia-iliaca (FI) Block Study
Hip Dysplasia · Femoroacetabular Impingement · Acetabular Labrum Tear
Primary: Visual Analog Scale — 2.65; 2.50 units on a scale
N/A N=52 Ultrasound Guided Adductor Canal Versus Femoral Nerve Blocks for Anterior Cruciate Ligament Reconstruction in Pediatrics
Post-operative Pain · Quadriceps Muscle Strength
Primary: Quadriceps Muscle Strength in Kilogram-force (Kgf) — 1.1; 0.0 Kilogram-force (Kgf) — p=0.026
Phase 2 N=192 Periarticular Injection Versus Peripheral Nerve Block in Total Hip Arthroplasty
Hip Arthropathy
Primary: Daily Opioid Consumption — 29.3; 30.8; 49.6; 51.8 milligram — p=0.69
Phase 4 N=114 Effects of Catheter Location on Postoperative Analgesia for Continuous Adductor Canal and Popliteal-Sciatic Nerve Blocks
Post-surgical Pain · Total Knee Arthroplasty · Foot/Ankle Surgery
Primary: Pain (Average): Numeric Rating Scale for Pain — 0.5; 3.0 score on a scale