N/A
N=57
Ventilation Strategies, Anesthetic Techniques and Cerebral Oxygenation in the Beach Chair Position
Stroke
Bottom Line
View on ClinicalTrials.gov: NCT01535274 ↗Enrolled (actual)
57
Serious AEs
0.0%
Results posted
Apr 2022
Primary outcome: Primary: Change in Regional Cerebral Oxygenation (rSO2) Before and 5 Minutes After Each Change in Ventilation Strategy — -4.27; -0.70; -15.48; -10.90 Percent oxygen saturation
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Inspired oxygen fraction / end tidal carbon dioxide (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of Michigan
- Primary completion
- Sep 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Regional Cerebral Oxygenation (rSO2) Before and 5 Minutes After Each Change in Ventilation Strategy |
-4.27; -0.70; -15.48; -10.90; -8.31; -3.14 | — |
| PRIMARY Regional Cerebral Oxygenation (rSO2) Values |
67; 69; 59; 62; 64; 67 | <0.001 sig |
Summary
The seated or "beach chair" position during surgery and general anesthesia decreases brain oxygen levels and can result in stroke. As such, poor neurological outcome following beach chair positioning is a growing concern. In the proposed study the investigators test the hypothesis that changes in ventilation strategy and anesthetic technique can affect cerebral oxygenation in anesthetized patients in the beach chair position.
Eligibility Criteria
Inclusion Criteria
- scheduled for elective arthroscopic shoulder surgery in the beach chair position under general anesthesia with supplemental interscalene block
Exclusion Criteria
- refusal to give consent
- ineligible for interscalene block
- history of cardiovascular disease
- history of cerebrovascular disease
- hypertension
- respiratory failure
- non-English speaker
Data sourced from ClinicalTrials.gov (NCT01535274). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.