Phase 4
N=250
Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women
Labor Pain
Bottom Line
View on ClinicalTrials.gov: NCT01555671 ↗Enrolled (actual)
250
Serious AEs
0.0%
Results posted
Sep 2021
Primary outcome: Primary: The Duration of Active Phase of Labour — 249; 304 minutes — p=0.029
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Meperidine (Drug); Saline (Drug)
- Age
- Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
- Primary completion
- May 2012
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Duration of Active Phase of Labour |
249; 304 | 0.029 sig |
| SECONDARY Total Duration of Labour |
273; 331 | — |
| SECONDARY Duration of the Second Stage of Labour |
24; 27 | — |
Summary
This study aims to evaluate the effect of meperidine on the length of active phase of labor in nulliparous or multiparous women, who will be randomized into two (control and study) groups. Our hypothesis is that the use of meperidine during active labor has no effect on the duration of labor.
Eligibility Criteria
Inclusion Criteria
- gestational age between 38 and 42 weeks
- live fetus
- cephalic presentation
- in active phase of labour
Exclusion Criteria
- placenta previa, placental abruption
- caesarean section or any uterine scarring
- multiple gestation
- fetal macrosomia (≥4000 g)
- meperidine allergy
- use any kind of labour induction or augmentation before on admission for delivery in our hospital
Data sourced from ClinicalTrials.gov (NCT01555671). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.