N/A
Completed N=5
Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation
Parkinson's Disease · Deep Brain Stimulation
Source: ClinicalTrials.gov NCT01563341 ↗
Enrolled (actual)
5
Serious AEs
20.0%
Results posted
Dec 2024
Primary outcomePrimary: Change in Memory Testing From Presurgical Baseline to 12 Months — 1 score on a scale
Summary
Does dual hemispheric stimulation of the subthalamic nucleus (STN) and fornix/hypothalamus potentially improve cognitive function in patients with Parkinsons disease.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Memory Testing From Presurgical Baseline to 12 Months |
1 | — |
Eligibility Criteria
Inclusion Criteria
- All patients will be enrolled from the practice of the primary investigator.
- Parkinson's Disease (PD) patients in whom optimal medical therapy has failed.
- All patients will have responsivity to levodopa.
- Individuals with normal or mild cognitive impairment.
Exclusion Criteria
- Clinically significant dementia
- Other significant neurological or psychiatric disease
- Previous brain surgery including pallidotomy or thalamotomy
- Previous placement of other implantable devices
Data sourced from ClinicalTrials.gov (NCT01563341). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.