Phase 2 N=10 Randomized Prevention

Inflammation, Polyphenols, and Genetics

Overweight · Obese

Bottom Line

View on ClinicalTrials.gov: NCT01568827 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Mar 2016

Primary outcome: Primary: Serum IL-6 — 42.4; 34.3 (pg*hr)/mL

Study Design & Population

Study type: Interventional
Phase: Phase 2
Interventions: Blackraspberry Slurry (Dietary_supplement)
Age: Adult, Older Adult · 55+ yrs
Sex: Male
Sponsor: Ohio State University
Primary completion: May 2012

Outcome Measures

Outcome	Result	p-value
PRIMARY Serum IL-6	42.4; 34.3	—

Summary

Pilot study to determine whether daily consumption of blackraspberry powder (high in polyphenols) can reduce markers of inflammation and to determine whether genetics influence baseline levels of inflammatory markers as well as individual's response to polyphenols. A total of 10 males participated in this cross-over study.

Eligibility Criteria

Inclusion Criteria

adult males over 55 years of age
overweight or obese

Exclusion Criteria

history of adverse reaction to berries or berry products
history of adverse reaction to high-fat, high-calorie challenge meal
significant liver or renal insufficiency
significant cognitive impairment

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01568827). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.