Oral white kidney bean extract reduces weight by 1.62 kg in adults with overweight or obesity compared to placebo
White kidney bean extract helps adults with overweight lose weight in this review
This systematic review and meta-analysis evaluated oral white kidney bean extract for weight management in adults with overweight or obesity…
A review of 543 adults found that taking white kidney bean extract led to weight loss and reduced body fat compared to a placebo.
Systematic review and meta-analysis of metformin for pediatric overweight and obesity shows modest BMI reduction
Metformin shows promise for weight management in children with overweight or obesity
This systematic review and meta-analysis evaluated metformin versus placebo in children with overweight or obesity across 19 original studie…
A meta-analysis of 19 studies suggests metformin may help lower BMI and weight in children with overweight or obesity compared to placebo.
Meta-analysis shows intermittent fasting lowers BMI and fasting glucose in women with overweight or obesity
Intermittent Fasting Works for Weight Loss But Has a Catch
This meta-analysis pooled data from 1287 participants to evaluate intermittent fasting in women with overweight or obesity. The analysis fou…
For women struggling with weight, intermittent fasting twice a week may lower body mass index and blood sugar, but don't expect it to fix yo…
Review of tart cherry effects in overweight and obesity reports inconsistent metabolic findings
Tart Cherries Show Promise for Blood Pressure in Overweight Adults
This narrative review synthesizes evidence on tart cherry products for overweight and obese individuals. It suggests potential benefits for …
Tart cherries could help lower blood pressure and fight inflammation in overweight adults, but don't expect them to melt away pounds just ye…
Bayesian network meta-analysis compares tirzepatide, liraglutide, and semaglutide for weight reduction in adults without diabetes
New Weight Loss Drug Beats Popular Options in Head-to-Head Comparison
This Bayesian network meta-analysis synthesized evidence from 42 randomized controlled trials, six of which were included in the network, to…
A newer weight loss drug helped people drop nearly 14 percent of their body weight, beating two popular options in a major comparison.
Systematic review links psycho-emotional and environmental factors to eating behaviors in adults with overweight or obesity
Young adults eat to cope with stress, not just hunger
This systematic review synthesizes evidence from 7,614 participants regarding factors associated with eating behaviors in young and middle-a…
Doctors now know that stress and emotions drive eating habits in young adults, so treating the mind helps manage weight.
Stand-alone digital lifestyle interventions show significant improvements in weight and dietary habits for adults with overweight or obesity compared to controls
Digital Tools Help Adults Lose Weight Without Human Support
A systematic review and meta-analysis of 19 studies involving 3,556 adults found that stand-alone digital lifestyle interventions significan…
New research shows that fully automated digital tools can help adults lose weight and eat better without needing a human coach or live suppo…
Wholegrain rye diets improve metabolic markers but not weight loss in overweight adults
Wholegrain rye lowers inflammation better than refined wheat for weight loss diets
This 12-week randomized trial compared hypocaloric diets with wholegrain rye versus refined wheat in 255 adults with overweight or obesity.
Switching to wholegrain rye while dieting may lower inflammation and improve gut bacteria even if weight loss is the same
Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
Oral sodium butyrate helps overweight adults without diabetes lose weight
This 12-week proof-of-concept RCT in 46 overweight adults (23 with type 2 diabetes) found that oral sodium butyrate 1875 mg/day led to great…
A new trial shows oral sodium butyrate helps adults without diabetes lose more weight than a placebo over three months.
Extended sleep improved sleep metrics but did not change insulin sensitivity in a small trial
Extended sleep improves sleep duration but not insulin sensitivity in small trial
This randomized trial investigated whether extending sleep duration improves metabolic health in people with overweight or obesity and habit…
In a small trial, people with overweight or obesity who slept longer stayed in bed more and felt better, but insulin sensitivity did not imp…
Afternoon/Evening Exercise May Lower Blood Pressure More Than Morning Exercise: Meta-Analysis
Evening exercise lowers blood pressure and sugar better than morning workouts for people with diabetes or high weight
This systematic review and meta-analysis of 625 participants found that afternoon/evening exercise (PmEx) was associated with significantly …
For people with type 2 diabetes or high blood pressure, working out in the afternoon or evening lowers blood pressure and sugar more than mo…
Bayesian network meta-analysis compares exercise modalities for systemic inflammation in postmenopausal women
Resistance training reduces inflammation in postmenopausal women
This Bayesian network meta-analysis of 39 RCTs evaluated the comparative efficacy of aerobic, resistance, HIIT, and combined training on inf…
New evidence suggests different types of exercise target different inflammatory markers in postmenopausal women with obesity.
Questions about Overweight
Did extending sleep duration change insulin sensitivity in people with overweight?
No, extending sleep by about 1 hour per night for 6 weeks did not change insulin sensitivity in people with overweight or obesity who were short sleepers.
Full answer →Do wholegrain rye diets help with weight loss in overweight adults?
Wholegrain rye diets do not lead to significantly more weight loss than refined wheat diets in overweight adults, but they improve metabolic markers like inflammation and gut health.
Full answer →Do stand-alone digital lifestyle interventions improve weight for adults with overweight?
Yes, stand-alone digital lifestyle interventions (fully automated apps or websites) lead to modest weight loss and improved dietary habits in adults with overweight or obesity, based on a 2026 meta-analysis.
Full answer →How does tirzepatide compare to semaglutide for weight reduction in adults without diabetes?
Tirzepatide leads to greater weight loss than semaglutide in adults without diabetes, based on network meta-analyses and cohort studies.
Full answer →All Overweight Articles
- Oral white kidney bean extract reduces weight by 1.62 kg in adults with overweight or obesity compared to placebo
- Systematic review and meta-analysis of metformin for pediatric overweight and obesity shows modest BMI reduction
- Review of tart cherry effects in overweight and obesity reports inconsistent metabolic findings
- Meta-analysis shows intermittent fasting lowers BMI and fasting glucose in women with overweight or obesity
- Bayesian network meta-analysis compares tirzepatide, liraglutide, and semaglutide for weight reduction in adults without diabetes
- Systematic review links psycho-emotional and environmental factors to eating behaviors in adults with overweight or obesity
- Stand-alone digital lifestyle interventions show significant improvements in weight and dietary habits for adults with overweight or obesity compared to controls
- Wholegrain rye diets improve metabolic markers but not weight loss in overweight adults
- Extended sleep improved sleep metrics but did not change insulin sensitivity in a small trial
- Afternoon/Evening Exercise May Lower Blood Pressure More Than Morning Exercise: Meta-Analysis
- Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
- Bayesian network meta-analysis compares exercise modalities for systemic inflammation in postmenopausal women
- GZR18 showed weight loss in Chinese adults with overweight or obesity in a phase 1b/2a trial
- Tirzepatide MTD Demonstrates Cost-Effectiveness Versus Semaglutide MTD in Obesity Simulation Modeling Study
- Theory-informed behavioural intervention reduces ultra-processed food intake and weight in UK adults
- Meta-analysis links ultra-processed food intake to higher odds of adolescent overweight/obesity
- Network meta-analysis finds metabolic surgery superior to GLP-1 agonists for weight loss in obesity
- Post-hoc analysis finds both continuous and intermittent calorie restriction reduce weight in type 2 diabetes
- Overweight status at diagnosis in Kuwaiti children with new-onset type 1 diabetes is associated with milder clinical presentation and lower HbA1c
- Full-fat dairy vs. low-fat dairy with energy restriction for weight and metabolic outcomes in adults with overweight/obesity
- Meta-analysis finds distinct neural activation patterns to food and monetary rewards in overweight/obesity
- Cognitive training add-on to behavioral weight-loss intervention shows moderate BMI reductions at 6 months
- Phase 1b trial of oral GLP-1 agonist HDM1002 shows weight reduction in Chinese adults with overweight/obesity
- Calorie restriction plus exercise reduced IL-6 and knee pain more than diet alone in knee OA
- GLP-1RAs reduce MACE risk in Asian and White adults with diabetes or overweight
- Prediabetes in youth with overweight/obesity associated with lower baseline cognition, stable over 2 years
- Horseshoe-like plantar hyperkeratosis associated with prediabetes in overweight adults
- Nutrition and health canteen intervention linked to weight reduction in middle-aged adults
- FDA Approves FOUNDAYO (orforglipron) for chronic weight management in adults with obesity or overweight with comorbidities
- Phase 1 trial of once-weekly eloralintide shows weight reduction in obesity over 12 weeks
- Tirzepatide improves patient-reported physical function in adults with overweight or obesity
- Network meta-analysis compares exercise types for insulin resistance in youth with overweight or obesity
- Mediterranean lifestyle intervention reduces BMI, fat mass in preschool girls at risk of obesity