Oral Sodium Butyrate Reduces Weight in Overweight Adults Without Diabetes
Oral sodium butyrate helps overweight adults without diabetes lose weight
This 12-week proof-of-concept RCT in 46 overweight adults (23 with type 2 diabetes) found that oral sodium butyrate 1875 mg/day led to great…
A new trial shows oral sodium butyrate helps adults without diabetes lose more weight than a placebo over three months.
Bayesian network meta-analysis compares exercise modalities for systemic inflammation in postmenopausal women
Resistance training reduces inflammation in postmenopausal women
This Bayesian network meta-analysis of 39 RCTs evaluated the comparative efficacy of aerobic, resistance, HIIT, and combined training on inf…
New evidence suggests different types of exercise target different inflammatory markers in postmenopausal women with obesity.
GZR18 showed weight loss in Chinese adults with overweight or obesity in a phase 1b/2a trial.
New Drug Cuts Weight by Nearly 20% in Just 35 Weeks
In this randomized, placebo-controlled phase 1b/2a trial, 60 Chinese adults with overweight or obesity received GZR18 or placebo. Over 26 to…
This new treatment shows huge promise for helping people reach their weight goals without daily pills.
Tirzepatide MTD Demonstrates Cost-Effectiveness Versus Semaglutide MTD in Obesity Simulation Modeling Study
Tirzepatide Saves Money and Health Over Semaglutide
This simulation modeling study using Phase-3 trial data evaluated tirzepatide versus semaglutide in individuals with obesity or overweight w…
Imagine standing in a doctor's office, facing a choice between two powerful weight-loss medicines.
Meta-analysis links ultra-processed food intake to higher odds of adolescent overweight/obesity
High ultra-processed food intake linked to higher obesity risk in teens
This systematic review and meta-analysis synthesizes evidence on ultra-processed food consumption and overweight/obesity in adolescents. It …
Teens who eat lots of ultra-processed foods have 63% higher odds of being overweight or obese compared to those with lower intake.
Theory-informed behavioural intervention reduces ultra-processed food intake and weight in UK adults
You Can Eat Better And Lose Weight By Swapping Foods
This exploratory single-arm pre-post study in 45 UK adults with overweight or obesity and habitual ultra-processed food (UPF) intake of at l…
A new plan to swap processed snacks for real food helps people lose weight and feel better.
Network meta-analysis finds metabolic surgery superior to GLP-1 agonists for weight loss in obesity
Weight-Loss Surgery Still Leads, But a New Medication Closes the Gap
A network meta-analysis of 20,015 adults with overweight or obesity compared metabolic/bariatric surgery, GLP-1 receptor agonists, and lifes…
Weight-loss surgery still beats drugs overall, but the newest medication tirzepatide closes the gap enough to matter for people who can't ha…
Post-hoc analysis finds both continuous and intermittent calorie restriction reduce weight in type 2 diabetes.
Two calorie-restricted diets helped people with type 2 diabetes lose weight in a small study.
A post-hoc analysis of RCTs in 67 people with type 2 diabetes and overweight or obesity compared 3-month continuous vs. intermittent calorie…
Two calorie-restricted diets helped people with type 2 diabetes lose weight and reduce fat while gaining muscle in a new study.
Overweight status at diagnosis in Kuwaiti children with new-onset type 1 diabetes is associated with milder clinical presentation and lower HbA1c.
Overweight Kids With Diabetes Have Milder Symptoms
This retrospective cohort study analyzed 1,265 children aged 14 years or younger newly diagnosed with type 1 diabetes in Kuwait. Results ind…
Being overweight changes how type 1 diabetes starts in children, making the early stage look different and easier to manage initially.
Full-fat dairy vs. low-fat dairy with energy restriction for weight and metabolic outcomes in adults with overweight/obesity
Full-Fat Dairy May Help Your Heart, Even Without Weight Loss
A 12-week RCT in 74 adults with overweight or obesity compared three daily servings of full-fat dairy to a low-fat dairy energy restriction …
Adding three daily servings of full-fat dairy improved blood pressure and diet quality in adults with overweight, offering heart benefits ev…
Meta-analysis finds distinct neural activation patterns to food and monetary rewards in overweight/obesity
Brain scans reveal how food and money rewards differ in people with overweight or obesity
A meta-analysis of 26 fMRI studies (1065 participants) found individuals with overweight/obesity show both overlapping and distinct neural a…
Researchers analyzed brain scan data from over 1,000 people to see how brains respond to food and money rewards. They found people with over…
Calorie restriction plus exercise reduced IL-6 and knee pain more than diet alone in knee OA
Small study finds adding exercise to calorie restriction may reduce knee pain and inflammation
A 4-week RCT in 23 overweight/obese adults with knee osteoarthritis compared calorie restriction alone to restriction plus aerobic exercise.…
Adding exercise to a calorie-reduced diet lowered knee pain and a specific inflammation marker in overweight people with knee osteoarthritis…