N/A
Completed N=100
Psychosis: Early Detection, Intervention and Prevention
Prodromal Schizophrenia · Psychotic disorders · Severe Bipolar Disorder With Psychotic Features · Severe Major Depression With Psychotic Features
Source: ClinicalTrials.gov NCT01597141 ↗
Enrolled (actual)
100
Serious AEs
2.0%
Results posted
Feb 2016
Primary outcomePrimary: Onset of Psychosis — 10; 14 percentage of sample converting
Summary
The primary aim of this application is to conduct a randomized, controlled clinical trial of a specialized mental health service delivery system specifically developed for prodromal psychotic disorders. The intervention is Family-aided Assertive Community Treatment (FACT). The goal of the treatment is prevention of psychosis and disability. This study will assess experimentally the clinical effectiveness of this new type of mental health service. Other domains of outcome include cognitive dysfunction and functional disability.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Onset of Psychosis |
10; 14 | — |
| SECONDARY Functioning |
59.83; 54.68 | — |
Eligibility Criteria
Inclusion Criteria
- Prodromal psychotic symptoms
- Age 12-35
- In catchment area (greater Portland, Maine)
Exclusion Criteria
- Previous or current psychotic episode
- IQ less than 70
- Outside catchment area
- Toxic psychosis
Data sourced from ClinicalTrials.gov (NCT01597141). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.